A Novel Methodology to Evaluate Health Impacts Caused by VOC Exposures Using Real-Time VOC and Holter Monitors

Mizukoshi, Atsushi; Kumagai, Kazukiyo; Yamamoto, Naomichi; Noguchi, Michihiko; Yoshiuchi, Kazuhiro; Kumano, Hiroaki; Yanagisawa, Yukio

doi:10.3390/ijerph7124127

Cited by 23 publications

(27 citation statements)

References 36 publications

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“…In our previous study, VOC exposure concentrations and HRV using VOC and Holter monitors were measured for seven healthy subjects [ 18 ]. In this study, we applied this method to MCS patients and identified characteristics of the relationship between VOC exposure, biological effects, and subjective symptoms in actual lives.…”

Section: Introductionmentioning

confidence: 99%

In-situ Real-Time Monitoring of Volatile Organic Compound Exposure and Heart Rate Variability for Patients with Multiple Chemical Sensitivity

Mizukoshi

Kumagai

Yamamoto

et al. 2015

IJERPH

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In-situ real-time monitoring of volatile organic compound (VOC) exposure and heart rate variability (HRV) were conducted for eight multiple chemical sensitivity (MCS) patients using a VOC monitor, a Holter monitor, and a time-activity questionnaire for 24 h to identify the relationship between VOC exposure, biological effects, and subjective symptoms in actual life. The results revealed no significantly different parameters for averaged values such as VOC concentration, HF (high frequency), and LF (low frequency) to HF ratio compared with previous data from healthy subjects (Int. J. Environ. Res. Public Health 2010, 7, 4127–4138). Significant negative correlations for four subjects were observed between HF and amounts of VOC change. These results suggest that some patients show inhibition of parasympathetic activities along with VOC exposure as observed in healthy subjects. Comparing the parameters during subjective symptoms and normal condition, VOC concentration and/or VOC change were high except for one subject. HF values were low for five subjects during subjective symptoms. Examining the time-series data for VOC exposure and HF of each subject showed that the subjective symptoms, VOC exposure, and HF seemed well related in some symptoms. Based on these characteristics, prevention measures of symptoms for each subject may be proposed.

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Section: Introductionmentioning

confidence: 99%

In-situ Real-Time Monitoring of Volatile Organic Compound Exposure and Heart Rate Variability for Patients with Multiple Chemical Sensitivity

Mizukoshi

Kumagai

Yamamoto

et al. 2015

IJERPH

Self Cite

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“…Odor pollution usually causes serious annoyance in urban areas because of the pungent smell and health hazards [ 1 ]. Usually, the composition of odor pollutants and their concentrations are various in different fields.…”

Section: Introductionmentioning

confidence: 99%

Research on Odor Interaction between Aldehyde Compounds via a Partial Differential Equation (PDE) Model

Yan¹,

Liu²,

Qu³

et al. 2015

Sensors

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In order to explore the odor interaction of binary odor mixtures, a series of odor intensity evaluation tests were performed using both individual components and binary mixtures of aldehydes. Based on the linear relation between the logarithm of odor activity value and odor intensity of individual substances, the relationship between concentrations of individual constituents and their joint odor intensity was investigated by employing a partial differential equation (PDE) model. The obtained results showed that the binary odor interaction was mainly influenced by the mixing ratio of two constituents, but not the concentration level of an odor sample. Besides, an extended PDE model was also proposed on the basis of the above experiments. Through a series of odor intensity matching tests for several different binary odor mixtures, the extended PDE model was proved effective at odor intensity prediction. Furthermore, odorants of the same chemical group and similar odor type exhibited similar characteristics in the binary odor interaction. The overall results suggested that the PDE model is a more interpretable way of demonstrating the odor interactions of binary odor mixtures.

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“…Small-scale exposure to VOCs causes ocular and throat irritation, vomiting, nausea, headache, loss of coordination, skin allergy [2][3][4], etc. Chronic effects that have been observed with VOCs include damage to the liver, lungs, kidney, reproductive system, respiratory system [5], and central nervous system in human beings. It is well known that some of the VOCs are carcinogenic [6,7] too.…”

Section: Introductionmentioning

confidence: 99%

Functionalized Carbon Nanotubes for Detection of Volatile Organic Pollutant

Rushi¹,

Datta²,

Ghosh³

et al. 2019

Perspective of Carbon Nanotubes

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Ever since carbon nanotubes were discovered, it has attracted researchers from all corners due to the fascinating characteristics they offer. Detection of environmental pollutants is one of the prominent sectors where carbon nanotubes have been extensively applied. Pristine carbon nanotubes attracted sincere attention at the initial phase; however, the inherent shortcomings as a chemical sensor were immediately recognized. Thereafter, improvement of selective and sensitive behavior of carbon nanotubes toward varied class of analytes has remained a core area of carbon nanotube-based research. Tailoring/covering sidewalls of carbon nanotubes with different functionalizing entities has shown remarkable outcomes in improving behavior of nanotube sensors in various domains. Organic conducting polymers, macrocyclic compounds, metal organic frameworks, metal nanoparticles, etc. have been extensively reported to functionalize carbon nanotube surface. This chapter discusses porphyrin-functionalized single-walled carbon nanotubes that are found to be selective toward volatile organic compounds, and most importantly, good selectivity and sensitivity have been observed for selected group of analytes.

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A Novel Methodology to Evaluate Health Impacts Caused by VOC Exposures Using Real-Time VOC and Holter Monitors

Cited by 23 publications

References 36 publications

In-situ Real-Time Monitoring of Volatile Organic Compound Exposure and Heart Rate Variability for Patients with Multiple Chemical Sensitivity

In-situ Real-Time Monitoring of Volatile Organic Compound Exposure and Heart Rate Variability for Patients with Multiple Chemical Sensitivity

Research on Odor Interaction between Aldehyde Compounds via a Partial Differential Equation (PDE) Model

Functionalized Carbon Nanotubes for Detection of Volatile Organic Pollutant

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