A Novel Method of CT Exophthalmometry in Patients With Thyroid Eye Disease

Tiong, Vincent Tze Yang; Sundar, Gangadhara; Makmur, Andrew; Yong, Clement; Wong, Yen Ling Jocelyn; Lang, Stephanie S; Tan, Ai Peng

doi:10.1097/01.apo.0000617908.29733.84

Cited by 2 publications

(3 citation statements)

References 19 publications

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“…Several different methods have been reported to measure proptosis using CT (22)(23)(24). We chose a classic method that measured the distance between the plane of the cornea and the orbital rim after reconstruction (11,25,26).…”

Section: Classic Radiological Exophthalmometry (Cr Method)mentioning

confidence: 99%

A novel method of measuring proptosis with computed tomography

Sun

Yin

et al. 2023

Acta Radiol

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Background Computed tomography (CT) can avoid interference factors and has been imported into some software to measure proptosis clinically as the golden standard. Purpose To establish a new method for semi-automatically measuring the proptosis on CT and evaluate its accuracy and reproducibility. Material and Methods A total of 50 orbital CT images were collected of healthy individuals, 25 patients with Graves ophthalmopathy (GO), and 25 patients with orbital fracture (OF). A new image processing software, MedrawHDC, was developed to semi-automatically measure the proptosis (MedrawHDC method). The classic radiological (CR) method (measuring proptosis with the software called Mimics) and MedrawHDC method were applied in all three groups (measured by observer S). Hertel's exophthalmometer (HE) method was also applied in the GO group. Moreover, two other observers were asked to measure the proptosis using MedrawHDC, to evaluate its reproducibility. Results The MedrawHDC method was highly consistent with the CR method in measuring proptosis (normal group: intraclass correlation coefficient [ICC] = 0.989; GO group: ICC = 0.979; OF group: ICC = 0.979). In the GO group, the value of proptosis measured by two radiological methods were consistent with that measured by the HE method (CR method: ICC = 0.703; MedrawHDC method: ICC = 0.697). Bland–Altman plots showed similar results. The measurements obtained by three observers were highly reproducible (ICC = 0.995). Conclusion The newly established MedrawHDC method, with high accessibility, convenience, and repeatability, is reliable in assessing proptosis. It shows high potential for wide application, having clinical value for scientific evaluation of proptosis.

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Section: Classic Radiological Exophthalmometry (Cr Method)mentioning

confidence: 99%

A novel method of measuring proptosis with computed tomography

Sun

Yin

et al. 2023

Acta Radiol

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“…It was obtained from the axial plane of the CT scan with single measuring line from tip of the posterior clinoid process to the posterior corneal surface of the globe. 6…”

Section: Methodsmentioning

confidence: 99%

“…It was obtained from the axial plane of the CT scan with single measuring line from tip of the posterior clinoid process to the posterior corneal surface of the globe. 6 Descriptive statistics were used to evaluate baseline characteristics with mean and SDs used for quantitative variables and counts and percentage for categorical variables. Continuous parametric data were analyzed by paired sample t test.…”

Section: Orbital Volume Measurement and Exophthalmometry Measurement ...mentioning

confidence: 99%

A Novel Patient-specific Titanium Mesh Implant Design for Reconstruction of Complex Orbital Fracture

Kittichokechai

Sirichatchai

Puncreobutr

et al. 2022

Plastic and Reconstructive Surgery - Global Open

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Background: Complex orbital fractures, including orbital rims and walls, require precise reconstruction. A titanium-based patient-specific implant (PSI) benefits over other implants when challenged with narrow surgical space and designable implant fixation point. Methods: This is a prospective noncomparative case series to evaluate the effect of complex orbital reconstruction using the newly designed lateral fixation patient-specific implant. The PSI was individually fabricated by 3D reconstruction using the mirrored nonaffected orbit as a template. The fixation point was at maxillary or zygomatic bone, depending on the bony remnant. Outcomes were obtained from computed tomography scan to compare orbital tissue volume and exophthalmometry value by posterior clinoid method before and after the surgery and also between both orbits in each patient. Results: Sixteen patients with complex orbital fracture with inferior orbital rim defect were enrolled. Seven were previously repaired with other implants. Compared with the preoperative measurement, the postoperative mean difference of orbital volume and exophthalmometry value between both eyes was significantly decreased (reduction of the mean difference of 2904.40 mm3; P < 0.001 and 2.89 mm; P < 0.001, respectively). The mean orbital volume and exophthalmometry value between affected and unaffected eyes were not different after surgical correction (P = 0.57 and P = 0.28, respectively). There was one infected wound from retained foreign body and one unresolved vertical diplopia after the reconstruction. Conclusions: Reconstruction of complex orbital fractures using the novel designed-PSI had excellent outcomes. Appropriate implant design with caution of orbital anatomy and placement techniques are keys for successful results.

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A Novel Method of CT Exophthalmometry in Patients With Thyroid Eye Disease

Cited by 2 publications

References 19 publications

A novel method of measuring proptosis with computed tomography

A novel method of measuring proptosis with computed tomography

A Novel Patient-specific Titanium Mesh Implant Design for Reconstruction of Complex Orbital Fracture

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