A novel method for sensitive, low-cost and portable detection of hepatitis B surface antigen using a personal glucose meter

Hitting the diagnostic sweet spot: Point-of-care SARS-CoV-2 salivary antigen testing with an off-the-shelf glucometer

“…A potential solution to this problem is to develop quantitative, rapid tests around infrastructure that has already been adopted in the market at-scale. It has been previously shown that commercial glucometers can be repurposed to detect a variety of non-glucose-based targets, quantitatively measuring cocaine, Ebola, hepatitis B, foodborne pathogens, and interferon-gamma (Chen et al, 2020;Du et al, 2015;Guo et al, 2020;Lan et al, 2015Lan et al, , 2016Taebi et al, 2018;Xiang and Lu, 2011;Zhang et al, 2019Zhang et al, , 2020. There are currently 422 million people worldwide who rely on these devices daily to manage their blood sugar, making the glucometer the most prevalent piece of diagnostic equipment globally (CDC, 2020d; "Diabetes Statistics).…”

Superparamagnetic α-Fe2O3/Fe3O4 Heterogeneous Nanoparticles with Enhanced Biocompatibility

“…Although MFe 2 O 4 nanoparticles have exhibited excellent characteristics in the biomedical field, their safe application in the human body is a major problem owing to the heavy metal elements presented in MFe 2 O 4 [1], which also limits their applications in the biomedical field. So, as one of the typical nanomaterials, spinel iron oxide nanoparticles without heavy metal elements have been widely applied in many aspects of the biomedicine field due to their good biocompatibility and no toxicity or low toxicity in organisms [2,3], such as magnetic resonance imaging (MRI) [4], clinical diagnosis and the treatment of diseases [5,6], magnetic carriers for drug targeting [7], catalysis [8][9][10][11][12], immune assays [13], targeting photodynamic therapy [14][15][16], cell separation [17], DNA extraction [18], and so on. Therefore, the preparations and applications of iron oxide nanoparticles have attracted more and more researchers [19,20].…”

Development and clinical evaluation of commercial glucose meter coupled with nanofiber based immuno-platform for self-diagnosis of SARS-CoV-2 in saliva

“…The development of quantitative, fast testing around infrastructure that has already been implemented at scale in the market might be a viable answer to these challenges. Commercial glucose meters have already been repurposed to detect several non-glucose-based targets, including cocaine, Ebola, hepatitis B, foodborne pathogens, and interferon-gamma [ [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] ]. The glucose meter is the most widely used piece of diagnostic equipment in the world, with 422 million individuals using it daily to monitor their blood sugar [ 40 ].…”