A novel LoC-SERS device integrated with aptamer recognition strategy for the highly sensitive and specific detection of thrombin and platelet-derived growth factor-B

Abstract

Detection of tumor biomarkers is of great significance for early diagnosis of cancer. Herein, we fabricated a novel lab-on-a chip surface-enhanced Raman scattering (SERS) (LoC-SERS) biosensing platform for highly sensitive...

A LoC-SERS platform based on triple signal amplification for highly sensitive detection of colorectal cancer miRNAs

“…For this reason, a LoC-SERS platform was developed by combining SERS technology and a microuidic chip (LoC). [20][21][22][23] On the one hand, SERS measurements have been greatly improved, with increased automation and reproducibility in the microuidic chip, reducing the human errors that tend to occur in measurements. On the other hand, the high sensitivity of SERS technology is fully suitable for micro-detection in microuidic chips.…”