2011
DOI: 10.1002/cncr.25843
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A novel KIF5B‐ALK variant in nonsmall cell lung cancer

Abstract: The discovery of the novel KIF5B-ALK variant further consolidated the role of aberrant ALK signaling in lung carcinogenesis.

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Cited by 86 publications
(60 citation statements)
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References 30 publications
(70 reference statements)
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“…Furthermore, in addition to EML4, the TRK-fused gene (TFG; refs. [4][5][6] and the kinesin family member 5B (KIF5B; refs. 4-6) have been described to be fused to ALK in rare cases (Table 1).…”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, in addition to EML4, the TRK-fused gene (TFG; refs. [4][5][6] and the kinesin family member 5B (KIF5B; refs. 4-6) have been described to be fused to ALK in rare cases (Table 1).…”
Section: Introductionmentioning
confidence: 99%
“…Finally, two different variants involving the KIF5B and ALK genes have been described in a small subset of NSCLC (Takeuchi et al 2009, Wong et al 2011.…”
Section: Alk In Epithelial Cancersmentioning
confidence: 99%
“…However, thirteen variants of EML4-ALK have been already described according to the break point on EML4 (from exon 2 to exon 20) [3]. Furthermore, beside EML4, TFG [1] and KIF5B [6,7] have also been described to be fused to ALK in rare cases. Thus, RT-PCR has to be multiplexed, i.e.…”
Section: Introductionmentioning
confidence: 96%