A novel FUT1*c.889C>T allele associated with the para‐Bombay AB phenotype and computational evaluation of the mutation effect

Abstract

Background: Mutation in the FUT1 gene can impact the structure and function of α-(1,2)-fucosyltransferase 1 (α2FucT1). To explain the para-Bombay phenotype of a novel FUT1 allele, three-dimensional (3D) modeling and mutation effect analysis of α2FucT1 were performed by bioinformatic tools.