A novel host restriction factor MRPS6 mediates the inhibition of PDCoV infection in HIEC-6 cells
Yuhang Jiang,
Guoqing Zhang,
Letian Li
et al.
Abstract:IntroductionPorcine deltacoronavirus (PDCoV) is a zoonotic pathogen with a global distribution, capable of infecting both pigs and humans. To mitigate the risk of cross-species transmission and potential outbreaks, it is crucial to characterize novel antiviral genes, particularly those from human hosts.MethodsThis research used HIEC-6 to investigate PDCoV infection. HIEC-6 cells were infected with PDCoV. Samples were collected 48 h postinfection for proteomic analysis.ResultsWe discovered differential expressi… Show more
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