A novel gas sampling introduction interface for fast analysis of volatile organic compounds using radiofrequency pulsed glow discharge time of flight mass spectrometry

Fandiño, Jonatan; Bouza, Marcos; Pisonero, Jorge; Blanco, Domingo; Sanz‐Medel, Alfredo; Bordel, N.

doi:10.1016/j.aca.2018.08.013

Cited by 7 publications

(9 citation statements)

References 18 publications

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“…The LOD values in the range of 0.5-5 ppb were achieved, which is perspective for the real application of the new approach for a wide range of analytical tasks, including the determination of VOCs in human exhalation. 15,16 When comparing our results with previous studies, 1,3,5 the following aspects may be identified. The combination of several factors related to the nature of the pulsed glow discharge resulted in the combination of two beneficial outcomes for the online detection mode, which are often hard to achieve together.…”

Section: No + + M → No + M +mentioning

confidence: 49%

“…Contrary to a previous study, 3 we introduced a supplementary argon flow into the discharge cell since the discharge could not be properly initiated without it. The increase of air pressure reduced the sensitivities of the VOCs and increased the intensity of the copper associates, as observed in our previous study.…”

Section: Resultsmentioning

confidence: 99%

“…1,2 Several studies addressed the application of glow discharge mass spectrometry (GDMS) in molecular analysis. [1][2][3][4][5] Fandino et al investigated two variants of GDMS application: as a detector in gas chromatography and under a continuous flow of VOCs (benzene, toluene, ethylbenzene, and xylene) in an artificial air mixture. 3 The afterglow of the discharge was used for the ionisation, employing mainly the Penning process.…”

Section: Introductionmentioning

confidence: 99%

“…Finally, the use of saturated vapours of VOCs was reported in the study. 3 It resulted in a concentration level 4-6 orders of magnitude higher than for human exhalation which potentially limits the use of [M+NO] + for the purpose of breath analysis.…”

Section: Introductionmentioning

confidence: 99%

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New Possibilities for the Determination of Volatile Organic Compounds by Their Molecular Ions in Air Using µs-Pulsed GD TOFMS

Gubal¹

2021

At.Spectrosc.

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A recent trend in glow discharge analysis, previously considered as a 'purely inorganic' technique, is related to the effective ionisation of volatile organic compounds (VOCs). This approach was demonstrated to be capable of analysing VOCs in both model gas mixtures and ambient air. In the current study, the possibility of the direct determination of VOCs of different classes of organic compounds (including toluene, p-xylene, chlorobenzene and 1,2,4-trimethylbenzene) in ambient air using microsecond pulsed glow discharge time-of-flight mass spectrometry (µs-Pulsed GD TOFMS) with copper hollow cathode was demonstrated. The ionisation processes with the formation of molecular ions M + , which can be used for quantification, were discussed. The fragmentation of detected molecular ions of VOCs was found to be quite low, which benefits both qualitative and quantitative determination. The ease of identification and relative simplicity of the mass spectrum is promising for the analysis of VOC mixtures. One of the possible applications of the designed method is the direct determination of VOCs in human exhaled breath for the diagnosis of lung diseases, including lung cancer. However, revealing its potential applicability for this purpose requires further research.

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Section: No + + M → No + M +mentioning

confidence: 49%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

New Possibilities for the Determination of Volatile Organic Compounds by Their Molecular Ions in Air Using µs-Pulsed GD TOFMS

Gubal¹

2021

At.Spectrosc.

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“…Fandino et al [ 21 ] used a Grimm cell for the ionization of VOCs with the detection in a time-of-flight mass spectrometer (TOFMS). Radiofrequency (13.6 MHz) packets with a duration of 40–50 µs and packet repetition frequency of 400 Hz were used for the ionization.…”

Section: Introductionmentioning

confidence: 99%

Volatile Organic Compound Fragmentation in the Afterglow of Pulsed Glow Discharge in Ambient Air

et al. 2022

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Glow discharge (GD) source gained an increased level of attention in relation to the analysis of volatile organic compounds (VOCs) since past work showed that this soft ionization method allowed direct analysis of VOCs with minimal fragmentation, however, the issue of fragmentation was not previously studied in detail. The aim of the present work was to investigate the effect of discharge conditions on VOC fragmentation in the system consisting of the cell with pulsed glow discharge and a time-of-flight mass spectrometer. Ionization of VOCs of different classes (hydrocarbons, alcohols, esters, and carboxylic acids) was investigated. A copper cathode with flat geometry was used. VOCs were ionized in the afterglow of short pulse glow discharge in the air. The use of discharge afterglow significantly reduces or eliminates the effects of ionization mechanisms other than Penning process, in particular, electron ionization. This significantly reduced VOC fragmentation and provided rather low limits of detection. Specific cluster formation was observed for alcohols and esters, which may facilitate their identification.

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Removal of Isopropanol by synergistic non-thermal plasma and photocatalyst

Lin

Liang

et al. 2022

Journal of Hazardous Materials

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A novel gas sampling introduction interface for fast analysis of volatile organic compounds using radiofrequency pulsed glow discharge time of flight mass spectrometry

Cited by 7 publications

References 18 publications

New Possibilities for the Determination of Volatile Organic Compounds by Their Molecular Ions in Air Using µs-Pulsed GD TOFMS

New Possibilities for the Determination of Volatile Organic Compounds by Their Molecular Ions in Air Using µs-Pulsed GD TOFMS

Volatile Organic Compound Fragmentation in the Afterglow of Pulsed Glow Discharge in Ambient Air

Removal of Isopropanol by synergistic non-thermal plasma and photocatalyst

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