A novel function of housefly glutathione S-transferase 6B-Its effect on the retention and increase of insecticidal activity of the insecticide prothiofos
Abstract:IntroductionGlutathione S-transferase (GST) conjugates many chemicals to glutathione (GSH) and is generally an enzyme in detoxification metabolism. In a living organism, increase of GST and its activity is, in many cases, one of the causes of the development of resistance to chemicals. In the case of organophosphorus (OP) insecticide, most of them are exposed to desalkylation and desarylation by GST possessed by OP-resistant insects, and their insecticidal activities are lost. However, prothiofos-like S-propyl… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.