A novel fluorescence-quenching immunochromatographic sensor for detection of the heavy metal chromium

Lateral flow assays: Principles, designs and labels

“…AuNPs, which have exceptional quenching ability, have been mostly used in fluorescence quenching immunoassay. The important advantages of these LFAs are the low background signal, high sensitivity and ability to label with multiple biorecognition elements [183].…”

Quantum dot based multiplex fluorescence quenching immune chromatographic strips for the simultaneous determination of sulfonamide and fluoroquinolone residues in chicken samples

“…The PVC sheet (30 cm  6 cm) was applied as the backing plate, and the NC membrane (2.5 cm wide) was placed on the center of the PVC sheet. FQICS were developed referring to the work reported by Fu et al and Shi et al, 25,29 and performed as following. OVA-QDs complexes were diluted with a suitable amount of 0.01 M, pH 7.4 PBS.…”

“…24 However, the uorescent particles have the peculiarity of sticking to the nitrocellulose (NC) membrane, due to their large size and tendency to agglomerate. 25 Futhermore, this kind of ICS with signal "turn off" mode, still suffers from relatively not high sensitivity because of requiring large amount of target analytes to eliminate the signals on the test (T) line. New immune chromatographic strip research efforts are focusing on the development of multi-analyte-residue analysis and the improvement of assay sensitivity.…”

“…Recently, some research groups [25][26][27][28][29][30] reported a novel uorescence-quenching ICS to improve the assay sensitivity. The uorescence donors used in the above study were mainly uo-rescein, uorescein-doped microspheres or Ru(phen) 3…”

Fluorescence quenching of rhodamine 6G by 1,3,5-Trinitroperhydro-1,3,5- triazine entrapped in porous sol–gel silica

“…The porosity of these matrices can make them capable of entrapping and immobilizing fluorescent dyes to sense different explosives. During the past decades, chemical sensors based on fluorescence quenching have been fabricated and studied in many laboratories [22][23][24][25]. To the best of our knowledge, there is no report on fluorescence quenching of rhodamine 6G by 1,3,5-Trinitroperhydro-1,3,5-triazine (RDX) in sol-gel matrix.…”