“…However, there are still several disadvantages of these widely reported sensors [ 19 ], e.g., the complex fabrication of SPR sensors, the cross-sensitivity towards temperature and RI of FBG sensors, etc. On the other hand, the optical fiber Fabry-Perot (FP) cavity sensor has the advantages of a simple detection principle, large detection range, and linear response [ 10 , 20 , 21 ], so it has wide applications in biosensing.…”
Blood glucose concentration is important for metabolic homeostasis in humans and animals. Many diabetic patients need to detect blood glucose daily which burdens community hospitals and family healthcare. Optical fiber sensors are widely used in biomedical detection because of their compact structure, fast response, high sensitivity, low cost, and ease of operation. In this work, we constructed a Fabry-Perot (FP) cavity biosensor for the fast detection of glucose concentration in serum. The femtosecond laser micromachining was applied to fabricate the FP cavity by printing the fiber-tip fixed-supported bridge at the end face of the optical fiber. An additional hemisphere was printed at the center of the outer surface of the bridge to avoid multi-beam interference. The results demonstrated that the proposed biosensor had high refractive index (RI) detection sensitivity, roughly 1039 nm/RIU at a wavelength of 1590 nm, and the detection sensitivity for glucose was around 0.185 nm/ (mg/mL) at a wavelength of 1590 nm. Due to its high sensitivity, compact structure, and fast response, the FP cavity biosensor has great potential to be applied in family healthcare for glucose concentration detection of diabetic patients.
“…However, there are still several disadvantages of these widely reported sensors [ 19 ], e.g., the complex fabrication of SPR sensors, the cross-sensitivity towards temperature and RI of FBG sensors, etc. On the other hand, the optical fiber Fabry-Perot (FP) cavity sensor has the advantages of a simple detection principle, large detection range, and linear response [ 10 , 20 , 21 ], so it has wide applications in biosensing.…”
Blood glucose concentration is important for metabolic homeostasis in humans and animals. Many diabetic patients need to detect blood glucose daily which burdens community hospitals and family healthcare. Optical fiber sensors are widely used in biomedical detection because of their compact structure, fast response, high sensitivity, low cost, and ease of operation. In this work, we constructed a Fabry-Perot (FP) cavity biosensor for the fast detection of glucose concentration in serum. The femtosecond laser micromachining was applied to fabricate the FP cavity by printing the fiber-tip fixed-supported bridge at the end face of the optical fiber. An additional hemisphere was printed at the center of the outer surface of the bridge to avoid multi-beam interference. The results demonstrated that the proposed biosensor had high refractive index (RI) detection sensitivity, roughly 1039 nm/RIU at a wavelength of 1590 nm, and the detection sensitivity for glucose was around 0.185 nm/ (mg/mL) at a wavelength of 1590 nm. Due to its high sensitivity, compact structure, and fast response, the FP cavity biosensor has great potential to be applied in family healthcare for glucose concentration detection of diabetic patients.
“…In recent years, various fiber-optic sensors have been reported, such as long-period fiber gratings [ 1 , 2 ], fiber Bragg gratings [ 3 , 4 , 5 , 6 ], Mach–Zehnder interferometer [ 7 , 8 , 9 , 10 , 11 ] and Michelson interferometer [ 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 ], etc. In 2020, JENS HØVIK et al [ 1 ] of Norwegian University developed a wavelength refractive index sensor based on long-period grating, and a response sensitivity of 5078 nm/RIU was measured from 1.33 RIU to 1.34 RIU.…”
Section: Introductionmentioning
confidence: 99%
“…In 2019, Wang, J. et al [ 14 ] fabricated a Michelson interferometer by splicing a single-mode fiber and a hollow silica tube, with a refractive index and temperature sensitivity of 8.1498 rad/RIU from 1.331 RIU to 1.387 RIU, and −0.05 rad/°C from 20 °C to 90 °C. In 2020, Qi K et al [ 15 ] of Harbin Institute of Technology proposed a fiber-optic Michelson interferometer based on a three-microsphere array, which measured a maximum temperature sensitivity of 115.3 pm/°C from 20 °C to 90 °C and a refractive sensitivity of −56.63 nm/RIU in the range of 1.3335 RIU to 1.406 RIU; the fabrication repeatability of the three microsphere structures of the sensor is difficult to control, and the repeatability of the process needs to be further enhanced.…”
An all-fiber temperature and refractive dual-parameter-sensing Michelson interferometer is designed based on the waist-enlarged bitaper. At 5 mm from the fiber end, the waist-enlarged bitaper is manually spliced and the probe is formed. Since the input light encounters the waist-enlarged bitaper, it will excite high-order modes to transmit in the fiber cladding, and there will be an optical path difference between the basic mode and the higher-order mode. The light transmitted in the core and cladding is reflected upon encountering the fiber end face and the interference occurs due to the optical path difference between basic mode and higher-order mode. Changes in temperature and refractive index at the fiber probe can be detected by monitoring the interference fringes. The refractive response sensitivity is −191.06 dBm/RIU from 1.351 RIU to 1.4027 RIU, and the temperature response sensitivity is 0.12 nm/°C from 11 °C to 98 °C. Through the sensitivity matrix equation, the superimposed refractive index and temperature signals can be effectively demodulated. The sensor has the advantages of multi-parameter measurement, compact structure, low cost, easy fabrication and high reliability.
“…Optical fiber wavelength-dependent sensors are divided into various types according to their structure, such as the fiber Michelson [ 5 ], U-shaped fiber sensor [ 6 , 7 ], coated fiber sensor [ 8 ], and Mach–Zehnder interferometer (MZI) [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ], etc. In 2019, Wang et al [ 5 ] developed a Michelson interferometer by splicing a single-mode fiber and a hollow quartz tube, based on a phase demodulation method, in the range of 1.331 RIU to 1.387 RIU; the refractive index response sensitivity is 8.1498 rad/RIU. The proposed sensor was compact and low-cost, but demodulation analysis was difficult, due to the Fourier analysis of the measurement results.…”
A Mach–Zehnder fiber optic sensor with high refractive index response sensitivity was developed. By fabricating a waist-enlarged bitaper structure on the interference arm of a single mode–multimode–single mode (SMS) Mach–Zehnder interferometer (MZI), the spectral contrast and response sensitivity were improved. Subsequently, the response sensitivity was further improved by etching the interference arm. When a beam of light was introduced into the sensor, due to the structural mismatch between the multimode fiber and the normal transmission light, the difference between the low-order mode and the high-order mode was generated in the fiber core and the fiber cladding. In the process of transmission in the sensing arm, due to the different refractive indices of the core and cladding, the optical path difference of the high-order mode and the low-order mode was different, which eventually generated interference fringes. The experimentally measured response sensitivity of SMS MZI in the range of 1.351 RIU to 1.402 RIU is 57.623 nm/RIU; the response sensitivity of a single mode–multimode–bitaper–multimode–single mode (SMBMS) MZI is 61.607 nm/RIU; and the response sensitivity of the etched SMBMS (ESMBMS) MZI is 287.65 nm/RIU. The response sensitivity of the new ESMBMS MZI is three times higher than that of the original SMS MZI. The sensor has the characteristics of compact structure, high sensitivity, easy manufacture, and a wide range of refractive index measurements, and can be used in food processing, pharmaceutical manufacturing and other fields.
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