A Novel Feature-Tracking Echocardiographic Method for the Quantitation of Regional Myocardial Function

Pirat, Bahar; Khoury, Dirar S.; Hartley, Craig J.; Tiller, Les; Rao, Liyun; Schulz, Daryl G.; Nagueh, Sherif F.; Zoghbi, William A.

doi:10.1016/j.jacc.2007.10.029

Cited by 252 publications

(208 citation statements)

References 15 publications

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“…compared to standard STI technology in that it has a smaller region of interest and combines ultrasound speckle with border tracking, 21 thereby enabling the tracking of endocardial (ENDO) and epicardial (EPI) motion separately. This capability allows independent quantification of myocardial deformation in ENDO and in EPI layers of LV, providing the opportunity to evaluate and estimate the physiological ENDO to EPI functional gradient.…”

Section: Myocardial Deformations In Amyloidosis and Hcmmentioning

confidence: 99%

Endocardial and Epicardial Deformations in Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

Bella

Minutoli

Pingitore

et al. 2011

Circ J

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Section: Myocardial Deformations In Amyloidosis and Hcmmentioning

confidence: 99%

Endocardial and Epicardial Deformations in Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

Bella

Minutoli

Pingitore

et al. 2011

Circ J

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“…3,4) In these myocardial deformations, diastolic left ventricular (LV) abnormalities are sensitive early signs of myocardial ischemia and have the additional advantage of persisting longer than ischemic-induced systolic dysfunction, [5][6][7] indicating diastolic strain might be superior to systolic strain for detecting the deformation of the myocardial ischemia area. Some previous studies [8][9][10] reported that peak systolic longitudinal strain (PSLS) was useful for detecting CAD at rest.…”

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confidence: 99%

Prediction of Coronary Artery Stenosis at Rest in Patients With Normal Left Ventricular Wall Motion

et al. 2013

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SummaryNoninvasive detection of coronary artery stenosis usually requires a stress test in patients without left ventricular (LV) regional wall motion abnormalities (RWMA). In contrast, abnormal regional LV relaxation caused by ischemia may persist beyond recovery from transient ischemia. The aim of the present study was to determine whether segmental analysis of abnormal regional LV relaxation using the strain imaging diastolic index (SI-DI) at rest could predict coronary artery stenosis in the three major vessels in patients without LV dysfunction or RWMA. We performed 2D speckle tracking echocardiography and coronary angiography in 85 patients without RWMA with suspected coronary artery disease. Patients with LV dysfunction or acute coronary syndrome were excluded. Echocardiographic images of the LV were obtained in the apical 2-, 3-, and 4-chamber views and divided into 6 segments. In each segment, SI-DI derived from transverse strain imaging was determined. Forty-eight patients had significant coronary artery stenosis (≥ 70%). The optimal cutoff values of SI-DI were 60.5% in the mid anteroseptal segment for detecting left anterior descending artery stenosis (sensitivity, 83.3%; specificity, 81.1%), 60.5% in the basal anterolateral segment for detecting left circumflex artery stenosis (sensitivity, 80.9%; specificity, 90.3%), and 61.5% in the basal inferior segment for detecting right coronary artery stenosis (sensitivity, 74.1%; specificity, 77.8%). A segmental analysis of SI-DI at rest predicted coronary artery stenosis in the three major vessels in patients without RWMA. This noninvasive method may be useful for detecting coronary artery stenosis without a stress test. (Int Heart J 2013; 54: 266-272)

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“…Strain assessment by this method was validated in an animal study against sonomicrometry. 9 Longitudinal systolic velocity, strain, and SR were recorded for lateral, septal, anterior, and inferior walls for each patient. Each wall was divided into basal, mid, and apical segments automatically.…”

Section: Velocity Vector Imagingmentioning

confidence: 99%

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2015

Exp Clin Transplant

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Objectives: Velocity vector imaging allows quantitation of myocardial strain and strain rate from 2-dimensional images based on speckle tracking echocardiography. The aim of this study was to analyze the changes in myocardial strain and strain rate patterns in patients with end-stage renal disease and renal transplant recipients. Materials and Methods: We studied 33 patients with end-stage renal disease on hemodialysis (19 men; mean age, 36 ± 8 y), 24 renal transplant recipients with functional grafts (21 men; mean age, 36 ± 7 y) and 26 age-and sex-matched control subjects. Longitudinal peak systolic strain and strain rate for basal, mid, and apical segments of the left ventricular wall were determined by velocity vector imaging from apical 4-and 2-chamber views. The average longitudinal strain and strain rate for the left ventricle were noted. From short-axis views at the level of papillary muscles, average circumferential, and radial strain, and strain rate were assessed. Results: Mean heart rate and systolic and diastolic blood pressure during imaging were similar between the groups. Longitudinal peak systolic strain and strain rate at basal and mid-segments of the lateral wall were significantly higher in renal transplant recipients and control groups than endstage renal disease patients. Average longitudinal systolic strain from the 4-chamber view was highest in control subjects (-14.5% ± 2.9%) and was higher in renal transplant recipients (-12.5% ± 3.0%) than end-stage renal disease patients (-10.2% ± 1.6%; P ≤ .001). Radial and circumferential strain and strain rate at the level of the papillary muscle were lower in patients with end-stage renal disease than other groups. Conclusions: Differences in myocardial function in patients with end-stage renal disease, renal transplant recipients, and normal controls can be quantified by strain imaging. Myocardial function is improved in renal transplant recipients compared with end-stage renal disease patients.

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A Novel Feature-Tracking Echocardiographic Method for the Quantitation of Regional Myocardial Function

Abstract: Velocity Vector Imaging, a new feature-tracking method, can accurately assess regional myocardial function at the endocardial level and is a promising clinical tool for the simultaneous quantification of regional and global myocardial function.

Cited by 252 publications

References 15 publications

Endocardial and Epicardial Deformations in Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

Endocardial and Epicardial Deformations in Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

Prediction of Coronary Artery Stenosis at Rest in Patients With Normal Left Ventricular Wall Motion

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