A novel EWSR1-MYB fusion in an aggressive advanced breast adenoid cystic carcinoma with mixed classical and solid-basaloid components

Lei, Ting; Shí, Yùzhēn; Da, Wenyue; Xia, Cunyan; Lei, Ting

doi:10.1007/s00428-023-03500-1

Virchows Arch

2023

DOI: 10.1007/s00428-023-03500-1

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A novel EWSR1-MYB fusion in an aggressive advanced breast adenoid cystic carcinoma with mixed classical and solid-basaloid components

Ting Lei

Yùzhēn Shí²,

Wenyue Da³

et al.

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2023

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Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature

Rypel,

Kubacka,

Mykała-Cieśla

et al. 2023

Medicina

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Breast cancer (BC) is a heterogeneous disease distinguished by four main subtypes based on the expression of estrogen, progesterone receptors, and human epidermal growth factor-2 on the cancer cells. Triple-negative breast cancer (TNBC) consists of approximately 10–20% of all BCs and is characterized by a poor prognosis. Adenoid cystic carcinoma (ACC) of the breast is a rare, special type of TNBC with low metastatic potential and usually favorable prognosis. There are no established recommendations concerning systemic therapy in advanced ACC. We present a case of a 70-year-old woman with locally advanced ACC with progression after radical mastectomy, and review the literature concerning the treatment of metastatic disease focused on systemic therapy.

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Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature

Rypel,

Kubacka,

Mykała-Cieśla

et al. 2023

Medicina

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A novel EWSR1-MYB fusion in an aggressive advanced breast adenoid cystic carcinoma with mixed classical and solid-basaloid components

Cited by 1 publication

References 17 publications

Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature

Locally Advanced Adenoid Cystic Carcinoma of the Breast—A Case Report with a Review of the Literature

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