“…based on a potentiometric measurement of molecular adsorption events on a gold electrode of an extended-gate FET sensor has been reported. 16 As a labeled enzyme, acetylcholinesterase (AChE) is a high-turnover enzyme, and has played the role of generating thiol compounds, which adsorb easily on the gold electrode. The interface potential on the gold electrode of the FET sensor has been shown to shift in the negative direction as a result of the adsorption of a thiol compound on the gold electrode, and the adsorption rate was related to the concentration of the antibody-antigen complex, i.e., the target in the sample.…”