A novel entry into 1,2,3,4,5,6-hexahydro-3-benzazocine-4,6-dione and 2-substituted-2,5,6,7-tetrahydro-4-benzazonine-1,3-(4H)-dione

Synthesis and stereochemistry of azeto[2,1-a]isoquinolin-2-one derivatives

“…1 Phenylacetic acid derivatives have been employed successfully for the preparation of bi-or tricyclic 2-azetidinones in only a few cases. [16][17][18][19][20] Occasionally, low yields are obtained 21 or the reaction does not lead to the expected β-lactam.…”

Three Distinct Reactions of 3,4-Dihydroisoquinolines with Azlactones: Novel Synthesis of Imidazoloisoquinolin-3-ones, Benzo[a]quinolizin-4-ones, and Benzo[d]azocin-4-ones

“…Various 1-substituted dihydroisoquinolines have been used for the synthesis of benzazocine, benzo[ a ]quinolizines, and thiazolo[2,3- a ]isoquinolin-3-ones 14 related to imidazoloisoquinolin-3-ones.…”