A novel electromagnetic mill promoted mechanochemical solid-state Suzuki–Miyaura cross-coupling reaction using ultra-low catalyst loading

Abstract

The Nobel-prize-winning Suzuki-Miyaura cross-coupling(SMC) is a practical and attractive strategy for the construction of C-C bonds in both academic and industrial settings. However, the development of solid-state SMC reactions remains...

Recent Development in the Catalytic Applications of Pd‐NHC (NHC=N‐Heterocyclic Carbene) Compounds in Amide C−N Activation Reactions

“…Additionally, the combination of new technologies needs further development. For example, the latest research has used ball mills [75] and electromagnetic mill machines [76] to avoid treating organic solvents. It is hoped that more green and efficient multifunctional catalytic systems will be designed and synthesized in the near future to solve the challenges associated with amide activation reactions.…”

Suzuki–Miyaura Coupling of Aryl Nosylates with Diethanolamine Boronates

“…The analytical data were in accordance with the literature. 24 Mp 69-71 °C. 1 H NMR (400 MHz, CDCl 3 ):  = 8.07 (d, J = 7.6 Hz, 2 H), 7.67 (d, J = 7.6 Hz, 2 H), 7.16 (d, J = 7.7 Hz, 2 H), 6.87 (td, J 1 = 1.5 Hz, J 2 = 8.8 Hz, 1 H), 2.67 (s, 3 H).…”

Electromagnetic mill promoted mechanochemical palladium-catalyzed solid state cyanation of aryl bromides using non-toxic K4[Fe(CN)6]

“…[38][39][40][41] Very recently, our group focused on developing novel electromagnetic mill promoted organic reactions, which could realize solid-state transformations without solvent or heating. 42,43 The success of solid-state Suzuki-Miyaura cross-coupling and solvent-free borylation of aryl bromides under the EMM conditions encouraged us to develop new transformations under this new concept.…”