A novel EIF3C-related CD8+ T-cell signature in predicting prognosis and immunotherapy response of nasopharyngeal carcinoma
Rui Li,
Yikai Wang,
Xin Wen
et al.
Abstract:Purpose
At present, dysfunctional CD8+ T-cells in the nasopharyngeal carcinoma (NPC) tumor immune microenvironment (TIME) have caused unsatisfactory immunotherapeutic effects, such as a low response rate of anti-PD-L1 therapy. Therefore, there is an urgent need to identify reliable markers capable of accurately predicting immunotherapy efficacy.
Methods
Utilizing various algorithms for immune-infiltration evaluation, we explored the role of EIF3C i… Show more
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