A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles

Abstract

Compound nanoparticle drug delivery system plays an important role in the interaction with lymph nodes. There are three primary types of lymphocytes: B cells, T cells, and natural killer cells. When the cells of the immune system turn carcinogenic, they assault body cells. The lymph fluid plays an important role in attacking healthy cells of the body; hence, this paper aimed to design a drug delivery system, which can efficiently direct nanoparticles to target the infected cells, helping in high-speed elimination of such cells. The proposed design depends on the interaction between these molecules, and the intelligent nano-controller has the ability to guide the nanoparticles by anaerobic contact. The proposed design proved that the smaller the nanoparticle size and density, the less dynamic viscosity of the liquid would be, which would reflect its resistance to flow. In addition, it was concluded that hydrogen molecules play a significant role in reducing lymphatic fluid resistance due to their low density.

Design and optimization of nano-antenna for thermal ablation of liver cancer cells

“…Nanotechnology has provided facilities for direct entry into tumors, ablation of cancer cells, and overcoming these challenges by increas-ing treatment efficiency. [6][7][8][9] One of the nanotechnology devices in the field of cancer treatment is the nano-antenna. The nano-antennas [10][11][12] are the metal nanostructures equivalent to radio-frequency and microwave antennas.…”

“…Among the various medical applications of the nano-antennas are bioassay, cell imaging, tissue delivery, cancer therapy, and radiation therapy. [8,[37][38][39] The radiation therapy process is based on the absorption of light by the tissue and its conversion into local heat. Therefore, in this treatment method, the temperature of cancer cells increased to a certain level of heat in the body, which is called hyperthermia.…”

“…[58,59] The simplest way to use the nano-antennas in cancer treatment is to use them as a drug delivery method. [8,32] One benefit of this method is the increased effectiveness of anticancer drugs injected into tumor tissues. In this procedure, a combination of the anticancer drugs and the nano-antennas are injecting into the tumor tissues.…”