A Novel Coumarin-Based Fluorescent Probe for the Detection of Hydrazine Both in Aqueous Solution and Vapor State

Abstract

A novel coumarin-based fluorescent probe CF was synthesized for the detection of hydrazine both in aqueous solution and vapor state with high sensitivity and selectivity. Upon addition of hydrazine, the solution of probe CF in MeCN-H2O (3/7, v/v, buffered CH3COOH/CH3COONa) at pH 5.0 exhibited a remarkable change in emission color from pale green to light blue, which could be recognized with naked eyes. Applied in weak acid condition, probe CF could detect hydrazine selectively with large amount of unknown environments according to the competing tests. Besides, with the limit of detection 8.32 ppb (2.6 × 10(-7) M), probe CF could well meet the request (10 ppb) of the U.S. Environmental Protection Agency (EPA).

Naked-Eye and Near-Infrared Fluorescence Probe for Hydrazine and Its Applications in In Vitro and In Vivo Bioimaging

“…15,25,40,50, 100, 150, 250, 500 µM) was added to CyJ (5 µM). And the fluorescence intensity of CyJ was nearly proportional to the hydrazine concentration range from 0 to 50 µM with R 2 = 0.996 and a standard deviation σ of 0.13 (Figure 2B).…”

Recent progress in the development of fluorescent probes for hydrazine

“…These spectral changes upon the addition of hydrazine can be easily observed by the naked eye. Two similar coumarin‐based fluorescent probes were also reported for the detection of hydrazine …”

Europium ion post-functionalized zirconium metal–organic frameworks as luminescent probes for effectively sensing hydrazine hydrate

“…13 In order to evaluate our sensing performance, we summarized most of the reported hydrazine detecting methods (Table 1). [38][39][40][41][42] It should be noted that chromatography methods generally possess much lower detecting limit, though they are usually time-consuming and costly. In the aspect of LOD, our method is comparable to other detecting methods.…”