A novel colorimetric and near-infrared fluorescence probe for detecting and imaging exogenous and endogenous hydrogen peroxide in living cells

Han, Hao; He, Xu; Wu, Minxing; Huang, Yibing; Zhao, Lihe; Xu, Lanlan; Ma, Pinyi; Sun, Ying; Song, Daqian; Wang, Xinghua

doi:10.1016/j.talanta.2020.121000

Cited by 26 publications

(7 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A new colorimetric near-infrared fluorescent probe (example 12) with an acetyl heterocyclic aromatic amine was designed by Wang’s group. 14 Heterocyclic aromatic amines have the advantages of a novel and simple chemical structure, large Stokes shift, and near-infrared emission wavelength. The identification group, acetyl, had the ability to enhance the ICT effects.…”

Section: Types Of H 2 O 2 Detec...mentioning

confidence: 99%

Recent Progress in Organic Small-Molecule Fluorescent Probe Detection of Hydrogen Peroxide

Xiao

Chen

et al. 2022

ACS Omega

View full text Add to dashboard Cite

The fluorescent probe has become an important method for accurate detection of H 2 O 2 , with advantages of simple operation, high sensitivity, good selectivity, and real-time dynamic monitoring. This paper reviews the research progress in organic small-molecule fluorescent probe H 2 O 2 detection methods that are based on different recognition reactions. In addition, the application prospect of fluorescent probes in the detection of trace H 2 O 2 is anticipated.

show abstract

Section: Types Of H 2 O 2 Detec...mentioning

confidence: 99%

Recent Progress in Organic Small-Molecule Fluorescent Probe Detection of Hydrogen Peroxide

Xiao

Chen

et al. 2022

ACS Omega

View full text Add to dashboard Cite

show abstract

“…[7] The excess of hydrogen peroxide can damage nucleic acids or proteins. [8] Due to diverse physiological and pathological roles of hydrogen peroxide [9] efficient and selective method for its detection is the major limitation on way to prevent the negative effects caused by hydrogen peroxide as well as diagnoses of relative diseases. Furthermore, hydrogen peroxide can be transformed into a more potent oxidant, or peroxy acid, which also can inactivate several regulatory enzymes such as protein tyrosine phosphatase.…”

Section: Introductionmentioning

confidence: 99%

Efficient Assay for the Detection of Hydrogen Peroxide by Estimating Enzyme Promiscuous Activity in the Perhydrolysis Reaction

Wilk

Ostaszewski

2021

ChemBioChem

View full text Add to dashboard Cite

Hydrogen peroxide is an ideal oxidant in view of its availability, atom economy, or green aspects. Furthermore, it is produced by the cell mitochondria and plays a meaningful role in controlling physiological processes, but its unregulated production leads to the destruction of organs. Due to its diverse roles, a fast and selective method for hydrogen peroxide detection is the major limitation to preventing the negative effects caused by its excess. Therefore, we aimed to develop an efficient assay for the detection of H 2 O 2 . For this purpose, we combined the enzymatic method for the detection of hydrogen peroxide with the estimation of the promiscuity of various enzymes. We estimated the activity of an enzyme in the reaction of pnitrophenyl esters with hydrogen peroxide resulting in the formation of peracid. To our knowledge, there is no example of a simple, multi-sensor demonstrating the promiscuous activity of an enzyme and detecting hydrogen peroxide in aqueous media.

show abstract

“…The traditional methods for the detection of H 2 O 2 include spectrophotometry [5], chemiluminescence [6,7], fluorescence [8,9] and high performance liquid chromatography [10]. However, these methods also have some limitations, such as expensive equipment and cumbersome procedures.…”

Section: Introductionmentioning

confidence: 99%

An Electrochemical Sensor Based on Chalcogenide Molybdenum Disulfide-Gold-Silver Nanocomposite for Detection of Hydrogen Peroxide Released by Cancer Cells

Zhang

et al. 2020

Sensors

View full text Add to dashboard Cite

Hydrogen peroxide (H2O2) as a crucial signal molecule plays a vital part in the growth and development of various cells under normal physiological conditions. The development of H2O2 sensors has received great research interest because of the importance of H2O2 in biological systems and its practical applications in other fields. In this study, a H2O2 electrochemical sensor was constructed based on chalcogenide molybdenum disulfide–gold–silver nanocomposite (MoS2-Au-Ag). Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and energy dispersive spectroscopy (EDS) were utilized to characterize the nanocomposites, and the electrochemical performances of the obtained sensor were assessed by two electrochemical detection methods: cyclic voltammetry and chronoamperometry. The results showed that the MoS2-Au-Ag-modified glassy carbon electrode (GCE) has higher sensitivity (405.24 µA mM−1 cm−2), wider linear detection range (0.05–20 mM) and satisfactory repeatability and stability. Moreover, the prepared sensor was able to detect the H2O2 discharge from living tumor cells. Therefore, this study offers a platform for the early diagnosis of cancer and other applications in the fields of biology and biomedicine.

show abstract

A novel colorimetric and near-infrared fluorescence probe for detecting and imaging exogenous and endogenous hydrogen peroxide in living cells

Cited by 26 publications

References 32 publications

Recent Progress in Organic Small-Molecule Fluorescent Probe Detection of Hydrogen Peroxide

Recent Progress in Organic Small-Molecule Fluorescent Probe Detection of Hydrogen Peroxide

Efficient Assay for the Detection of Hydrogen Peroxide by Estimating Enzyme Promiscuous Activity in the Perhydrolysis Reaction

An Electrochemical Sensor Based on Chalcogenide Molybdenum Disulfide-Gold-Silver Nanocomposite for Detection of Hydrogen Peroxide Released by Cancer Cells

Contact Info

Product

Resources

About