Abstract:Object: Explore the specific function of CCR7 in immune mechanism of LIHC, and constructed CCR7-related immune prognostic signature (IPS) for LIHC patients.Methods: The RNA-seq data of LIHC was downloaded from TCGA dataset and the samples were divided into CCR7_H and CCR7_L group. Then, ssGSEA analysis, immune microenvironment analysis, expression level analysis of HLA genes and check point genes were conducted. The differential expression immune genes (DEIGs) were conducted and LASSO Cox was applied to constr… Show more
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