A Novel Cause of Inferior Olivary Hypertrophy

Oculopalatal Tremor Following Pontine Hemorrhage

“…Hypertrophic olivary degeneration, thought to be instrumental for the development of symptomatic OPT 1 (in contradistinction to essential palatal tremor with which there is no associated underlying lesion), most commonly results following stroke (hemorrhagic more often than ischemic), although strategic demyelinating lesions or tumors involving the dentatorubral–olivary pathway have also been reported. 2,3 Symptomatic OPT is not apparent at the time of ictus but rather emerges several months to years later. 4 Timely recognition of this constellation of clinical signs prompts the requisite neuroimaging to diagnose symptomatic OPT and guide treatment of the underlying lesion if warranted.…”