A novel biofabrication of gold nanoparticles using Erythrina senegalensis leaf extract and their ameliorative effect on mycoplasmal pneumonia for treating lung infection in nursing care

Abstract

This study showed the fabrication of gold nanoparticles (AuNPs) utilizing Erythrina senegalensis leaf extract as an effective, low-cost and eco-friendly approach. The bioconstituents existing in the E. senegalensis leaf extract are accountable for reducing and stabilization of NPs. The produced AuNPs were studied by using transmission electron microscopy, X-ray diffraction, UV-visible (UV-Vis) spectroscopy, Fourier transform infrared spectroscopy and energy-dispersive X-ray spectroscopy. In addition, this study also showed that the prepared AuNPs exhibited very good antipneumonial activity against mycoplasmal pneumonia in the investigational animals, indicating their potential for the development of new therapeutic drugs for the lung injury treatments in in the future.