A novel assay for detecting canine parvovirus using a quartz crystal microbalance biosensor

Kim, Yong Kwan; Lim, Suk-Kyung; Choi, Sarah; Cho, In‐Soo; Park, Eun-Hye; An, Dong-Jun

doi:10.1016/j.jviromet.2015.03.015

Cited by 17 publications

(14 citation statements)

References 45 publications

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“…Gold nanoparticle-based immunochromatographic strip test using a combination of mAb and pAb was developed as an alternative for on-site and cost-effective diagnosis of CPV infection . Another use of biotechnology has been observed for rapid and early detection of CPV using a QCM biosensor (Kim et al, 2015). Also, for genotyping of CPV-2, conventional methods are time consuming, therefore, a probe-based duplex fluorescence melting curve analysis (FMCA) for genotyping six different CPV-2 variants (original CPV-2, CPV-2a, CPV-2b, CPV-2c, and vaccine strains of CPVpf and CPVint) using only two Taqman probes has been developed (Liu et al, 2019).…”

Section: Biotechnological Tools In Companion Animals' Disease Diagnosismentioning

confidence: 99%

Biotechnological innovations in farm and pet animal disease diagnosis

Malik

Verma

Kumar

et al. 2020

Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries

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Section: Biotechnological Tools In Companion Animals' Disease Diagnosismentioning

confidence: 99%

Biotechnological innovations in farm and pet animal disease diagnosis

Malik

Verma

Kumar

et al. 2020

Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries

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“…This requires the modification of Au-electrodes by functional thiols which can bind to the electrode surface More recently, a few reports revealed the rapid diagnosis of H3N2 canine influenza virus (CIV) and canine parvovirus (CPV) with the help of NAb-QCM biosensors [95,100]. Kim et al [95] immobilized antibodies on gold-coated QCM surface using a calixcrown derivative, ProLinker™ B.…”

Section: Dna and Aptamers For Qcm Virus Sensorsmentioning

confidence: 99%

Gravimetric Viral Diagnostics: QCM Based Biosensors for Early Detection of Viruses

et al. 2017

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Viruses are pathogenic microorganisms that can inhabit and replicate in human bodies causing a number of widespread infectious diseases such as influenza, gastroenteritis, hepatitis, meningitis, pneumonia, acquired immune deficiency syndrome (AIDS) etc. A majority of these viral diseases are contagious and can spread from infected to healthy human beings. The most important step in the treatment of these contagious diseases and to prevent their unwanted spread is to timely detect the disease-causing viruses. Gravimetric viral diagnostics based on quartz crystal microbalance (QCM) transducers and natural or synthetic receptors are miniaturized sensing platforms that can selectively recognize and quantify harmful virus species. Herein, a review of the label-free QCM virus sensors for clinical diagnostics and point of care (POC) applications is presented with major emphasis on the nature and performance of different receptors ranging from the natural or synthetic antibodies to selective macromolecular materials such as DNA and aptamers. A performance comparison of different receptors is provided and their limitations are discussed.

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“…QCM biosensor was 95.4 % sensitive and 98% specific compared to PCR. It is rapid and accurate clinical diagnostic tool for CPV infection (Kim et al, 2015).…”

Section: Recent Diagnostic Techniquesmentioning

confidence: 99%

Current Scenario and Future Perspectives of CPV-2 Vaccines in India

Kadı¹,

Rathnamma²,

Narayanaswamy³

et al. 2017

Adv. Anim. Vet. Sci.

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| Canine parvovirus causes acute hemorrhagic gastroenteritis in canines. It is prone to genetic evolution and has undergone several mutations that have led to various antigenic variants of CPV-2.Vaccination is the most cost-effective and ideal method to control the canine parvovirus infections. Both live attenuated and inactivated vaccines are available to control the disease in animals. Vaccines used during the late 1970s and early 1980s were of feline panleukopenia virus (FPV) origin, which was followed by the use of inactivated and live attenuated vaccines of CPV-2 canine origin. Hightiter and low-passage CPV vaccines containing a canine-origin attenuated virus are currently considered vaccines-ofchoice for use in pups of any breed. Vaccination is likely to be successful when the maternal antibody titer has declined to less than 1:10. Titers below 1:40 are variably protective, but they may interfere with vaccination. Strain difference between field virus and vaccine candidate virus could be one of the important attributable reasons for immunization failure in the country. The high rate of infection in both vaccinated and unvaccinated dogs raise questions on relevance of the present day vaccines, which in most countries contain old variants. Though some believe that the heterologous protection offered by these old strains against the new variants is good enough, a growing proportion think that the time has come to manufacture vaccines incorporating the variants prevalent in a country.

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A novel assay for detecting canine parvovirus using a quartz crystal microbalance biosensor

Cited by 17 publications

References 45 publications

Biotechnological innovations in farm and pet animal disease diagnosis

Biotechnological innovations in farm and pet animal disease diagnosis

Gravimetric Viral Diagnostics: QCM Based Biosensors for Early Detection of Viruses

Current Scenario and Future Perspectives of CPV-2 Vaccines in India

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