A Novel Artificial Vitreous Substitute - Foldable Capsular Vitreous Body

Gao, Qianying

doi:10.5772/28687

Cited by 1 publication

(2 citation statements)

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“…Our previously reported FCVB was formed using a dipping technology,19 but was unable to closely mimic the shape of the rabbit vitreous. In this study, the FCVB was fabricated by an injection forming technology, which used a specially designed mirror steel mold that consisted primarily of an upper composite die, a lower composite die, and the core 23. The core shape could be manipulated via computer according to the vitreous parameters of a rabbit.…”

Section: Methodsmentioning

confidence: 99%

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Clinical device‐related article evaluation of morphology and functions of a foldable capsular vitreous body in the rabbit eye

et al. 2011

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We previously proposed a new strategy to replace a vitreous body with a novel foldable capsular vitreous body (FCVB). In this study, the FCVB was designed to mimic natural vitreous morphology, and evaluate its physiological functions compared with traditional silicone oil substitutes, in an established rabbit model of proliferative vitreoretinopathy. We found that FCVB was a very good replacement for closely mimicking the morphology and restoring the physiological functions, such as the support, refraction, and cellular barriers, of the rabbit vitreous body. The study has provided us with a novel research and therapy strategy that could effectively mimic the morphology and physiological function of the rabbit vitreous body.

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Section: Methodsmentioning

confidence: 99%

“…The gaps between the dies and the core could be adjusted to control the thickness of the FCVB's capsule (Figure 1). 23…”

Section: Methodsmentioning

confidence: 99%