A novel APD-based detector module for multi-modality PET/SPECT/CT scanners

Saoudi, A.

doi:10.1109/23.775566

Cited by 101 publications

(19 citation statements)

References 13 publications

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“…Furthermore, the electrical noise produced by components of PET detectors, such as PMTs, may induce significant artifacts in MRI. One solution to this problem is to replace the PMTs with avalanche photodiodes (APDs) [4,5]. These devices are relatively unaffected by the presence of magnetic fields, so they are preferred candidates for application to MRI-PET systems.…”

Section: Introductionmentioning

confidence: 99%

Initial tests of a prototype MRI-compatible PET imager

Raylman

Majewski

Lemieux

et al. 2006

Nuclear Instruments and Methods in Physics Research Section A:

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Section: Introductionmentioning

confidence: 99%

Initial tests of a prototype MRI-compatible PET imager

Raylman

Majewski

Lemieux

et al. 2006

Nuclear Instruments and Methods in Physics Research Section A:

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“…As a result, both emission techniques are not mutually exclusive and it has even been shown that in some particular situations, simultaneous acquisitions may have advantages over separate acquisitions [4]. These facts have motivated several authors to design combined PET/SPECT systems [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Performance analysis of a low-cost small animal PET/SPECT scanner

Guerra

Rubio

Ortuño

et al. 2007

Nuclear Instruments and Methods in Physics Research Section A:

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“…One approach to solving this problem is to replace the PMTs with avalanche photodiodes (APD) [1][2][3]. APDs are solid-state devices that have moderate gain, but are virtually unaffected by strong magnetic fields.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous acquisition of magnetic resonance spectroscopy (MRS) data and positron emission tomography (PET) images with a prototype MR-compatible, small animal PET imager

Raylman

Majewski

Velan

et al. 2007

Journal of Magnetic Resonance

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Multi-modality imaging (such as PET-CT) is rapidly becoming a valuable tool in the diagnosis of disease and in the development of new drugs. Functional images produced with PET, fused with anatomical images created by MRI, allow the correlation of form with function. Perhaps more exciting than the combination of anatomical MRI with PET, is the melding of PET with MR spectroscopy (MRS). Thus, two aspects of physiology could be combined in novel ways to produce new insights into the physiology of normal and pathological processes. Our team is developing a system to acquire MRI images and MRS spectra, and PET images contemporaneously. The prototype MR-compatible PET system consists of two opposed detector heads (appropriate in size for small animal imaging), operating in coincidence mode with an active field-of-view of approximately 14 cm in diameter. Each detector consists of an array of LSO detector elements coupled through a 2-m long fiber optic light guide to a single position-sensitive photomultiplier tube. The use of light guides allows these magnetic field-sensitive elements of the PET imager to be positioned outside the strong magnetic field of our 3T MRI scanner. The PET scanner imager was integrated with a 12-cm diameter, 12-leg custom, birdcage coil. Simultaneous MRS spectra and PET images were successfully acquired from a multi-modality phantom consisting of a sphere filled with 17 brain relevant substances and a positron-emitting radionuclide. There were no significant changes in MRI or PET scanner performance when both were present in the MRI magnet bore. This successful initial test demonstrates the potential for using such a multi-modality to obtain complementary MRS and PET data.

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A novel APD-based detector module for multi-modality PET/SPECT/CT scanners

Cited by 101 publications

References 13 publications

Initial tests of a prototype MRI-compatible PET imager

Initial tests of a prototype MRI-compatible PET imager

Performance analysis of a low-cost small animal PET/SPECT scanner

Simultaneous acquisition of magnetic resonance spectroscopy (MRS) data and positron emission tomography (PET) images with a prototype MR-compatible, small animal PET imager

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