A novel antimicrobial composite: ZnAl-hydrotalcite with <i>p</i>-hydroxybenzoic acid intercalation and its possible application as a food packaging material

Cheng, Huimin; Gao, Xue-Wei; Zhang, Kang; Wang, Xinrui; Zhou, Wei; Li, Shujing; Cao, Xueli; Yan, Dongpeng

doi:10.1039/c9nj03943k

Cited by 28 publications

(10 citation statements)

References 33 publications

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“…P-hydroxybenzoic acid has been isolated from various sources including plants as well as microbes as a strong antimicrobial compound. [39,40] p-hydroxybenzoic acid is mostly used in commetics, food, and pharmaceutical industries as a most potent preservatives because of their broad range of antibacterial activity. [41] Phytol is a dipertene member of acyclic alcohols detected in the extract of Ajwa dates.…”

Section: Resultsmentioning

confidence: 99%

Phenolic profiling and antibacterial potential of Saudi Arabian native date palm (Phoenix dactylifera) cultivars

Mediani

2020

International Journal of Food Properties

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Date Palm (Phoenix dactylifera) is one of the important fruit enriched with an impressive list of essential nutrients and a wide range of phenolic compounds with high antibacterial compounds. In order to provide further detailed information on phenolic compounds and antibacterial activities of Date Palm (Phoenix dactylifera), the current study was devoted to investigate and compare three different highly consumable varieties of date palm (Phoenix dactylifera) cultivars, namely Ajwa, Khalas Alkharj, and Al-Qasim for their broad spectrum antibacterial effect and phenolic compounds. The antibacterial properties of their methanolic extracts were evaluated against Streptococcus pnuemoniae, Bacillus subtilis, Klebsiella pneumonia, Staphylococcus aureus, Escherichia coli. All of the three cultivars displayed a broad spectrum of inhibitory effect against these pathogenic bacteria. Moverover, the LC-Linear Ion Quadrupole Mass Spectrometric Analysis (LC-MS and LC-MS/MS Tandem Mass Spectrometry) analysis revealed the presence of 3,30-di-O-methyl ellagic acid, 7-Methoxyquercetin-O-hexose isomers, caffeic acid, ferulic acid, isomers of quercentin-rutinoside, kaempferol methylether, p hydroxybenzoic acid, phytol, punicalagin and quercetin-3-O-glucoside (isoquercitrin) were in Ajwa, 3,30-di-O-methyl ellagic acid isomers, 3,30-di-O-methyl ellagic acid, caffeic acid derivative, cafeic acid, caffeoyl glucose, caffeoylshikimic acid, ferulic acid, guaiacyl(8-5)ferulic acid hexoside isomer, isorhamnetin-3-Ohexoside, oxooctadecanoic acid, punicalagin and quercetin derivativein Al-Qasim extracts while 2(3,4-Dihydroxyphenyl)-7-hydroxy-5-benzene propanoic acid isomer, 2 (3,4-Dihydroxyphenyl)-7-hydroxy-5-benzene propanoic acid, decanoic acid derivative, diosmetin, kaempferol-3-rutinoside, linolenic acid, oxooctadecanoic acid conjugate and punicalagin in the extract of Khalas date. The findings of the current study may increase our knowledge about the importance of dates in diet and can be utilized as natural antimicrobial agents in the foods industry. ARTICLE HISTORY

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Section: Resultsmentioning

confidence: 99%

Phenolic profiling and antibacterial potential of Saudi Arabian native date palm (Phoenix dactylifera) cultivars

Mediani

2020

International Journal of Food Properties

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“…Cheng et al incorporated p -hydroxybenzoic acid (PHBA) into ZnAl-LDHs to inhibit the growth of S. aureus and Candida albicans . 423 It was found that PHBA/ZnAl-LDHs continuously released PHBA in acidic environment, which could be attributed to the enhanced solubility of PHBA by protonation. Likewise, Tang et al embedded dl -mandelic acid (MA) into ZnAl-LDHs through an ion exchange reaction.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Layered double hydroxide-based nanomaterials for biomedical applications

et al. 2022

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“…Furthermore, the organo-modification of LDH improves the compatibility with polymer matrices, thus making LDHs particularly interesting and versatile as additives for polymer composites. Modification of LDH with salicylate anions [150] and benzoic acid derivatives [151][152][153], known for antibacterial properties, is described in the literature. Additionally, these functional fillers have successfully dispersed in various polymer matrices, demonstrating that the functional host-guest systems slowly release their contents to maintain antimicrobial agent concentrations at desired levels over a long period of time.…”

Section: Bionanosystems Based On Inorganic Carriersmentioning

confidence: 99%

Rosmarinic Acid and Ulvan from Terrestrial and Marine Sources in Anti-Microbial Bionanosystems and Biomaterials

et al. 2021

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In order to increase their sustainability, antimicrobial renewable molecules are fundamental additions to consumer goods. Rosmarinic acid is extracted from several terrestrial plants and represents an effective anti-microbial agent. Ulvan, extracted from algae, is an anti-microbial polysaccharide. The present review is dedicated to discussing the sources and the extraction methodologies for obtaining rosmarinic acid and ulvan. Moreover, the preparation of bioanosystems, integrating the two molecules with organic or inorganic substrates, are reviewed as methodologies to increase their effectiveness and stability. Finally, the possibility of preparing functional biomaterials and anti-microbial final products is discussed, considering scientific literature. The performed analysis indicated that the production of both molecules is not yet performed with mature industrial technologies. Nevertheless, both molecules could potentially be used in the packaging, biomedical, pharmaceutical, cosmetic, sanitary and personal care sectors, despite some research being required for developing functional materials with specific properties to pave the way for many more applications.

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A novel antimicrobial composite: ZnAl-hydrotalcite with p-hydroxybenzoic acid intercalation and its possible application as a food packaging material

Abstract: p-Hydroxybenzoic acid was intercalated into LDHs (Zn/Al ratio = 4 : 1). The former possesses anti-fungal activity and the latter shows the best antibacterial effect.

Cited by 28 publications

References 33 publications

Phenolic profiling and antibacterial potential of Saudi Arabian native date palm (Phoenix dactylifera) cultivars

Phenolic profiling and antibacterial potential of Saudi Arabian native date palm (Phoenix dactylifera) cultivars

Layered double hydroxide-based nanomaterials for biomedical applications

Rosmarinic Acid and Ulvan from Terrestrial and Marine Sources in Anti-Microbial Bionanosystems and Biomaterials

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