A novel and efficient synthesis of pyrazolo[3,4-d]pyrimidine derivatives and the study of their anti-bacterial activity

Rostamizadeh, Shahnaz; Nojavan, Masoomeh; Aryan, Reza; Sadeghian, Hamid; Davoodnejad, Mahdieh

doi:10.1016/j.cclet.2013.04.035

Cited by 52 publications

(22 citation statements)

References 18 publications

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“…Pyrimidines are an integral part of DNA and RNA and exhibit diverse pharmacological properties such as antibacterial, 382 antifungal 383 and antiviral activities. 384 Certain pyrimidines and annulated pyrimidine derivatives are also known to display anticancer, [385][386] antimalarial, 387 antileishmanial 388 and antifilarial activities.…”

Section: Pyrimidinesmentioning

confidence: 99%

Ninhydrin in synthesis of heterocyclic compounds

Ziarani¹,

Lashgari²,

Azimian³

et al. 2015

Arkivoc

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Ninhydrin has been utilized in many heterocyclic preparations and considered as an important building block in organic synthesis. There is a wide range of reactions that include ninhydrin in the synthesis of heterocyclic compounds. This review highlights the advances in the use of ninhydrin as starting material in the synthesis of various organic compounds and drugs in a fully comprehensive way, from its first isolation in 1910 to the end of 2013. There is also a diversity of multi-component reactions of ninhydrin and we highlight the recent reports in this review.

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Section: Pyrimidinesmentioning

confidence: 99%

Ninhydrin in synthesis of heterocyclic compounds

Ziarani¹,

Lashgari²,

Azimian³

et al. 2015

Arkivoc

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“…The products 50a-m were all prepared with excellent yields at 100 O C in 1-1.5 h. Both aromatic aldehydes with electron donating substituents and electron-withdrawing substituents showed significant reactivity in this process 65. The products 50a-m were all prepared with excellent yields at 100 O C in 1-1.5 h. Both aromatic aldehydes with electron donating substituents and electron-withdrawing substituents showed significant reactivity in this process 65.…”

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confidence: 95%

Synthesis of heterocycles and fused heterocycles catalyzed by nanomaterials

Elwahy

Shaaban

2015

RSC Adv.

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“…This scaffold shows a broad spectrum of biological activities. The thienopyrimidines were assessed as antitumour [6][7][8][9], medicine [10], enzyme [11][12][13][14], phosphodiesterase inhibitors [15], antioxidative [16,17], antimalarial drug [18,19], antibacterial drug [20], antiviral [21], antifungal [22,23], medication [24], antiplatelet [25] and medicament [26]. In view of these observations, the varied biological property of thienopyrimidine pharmacophore impelled to synthesize the title compounds.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Antibacterial Activity of Thienopyrimidine Amide Derivatives

Tharikoppula¹,

Eppakayala²,

Chary³

et al. 2017

Asian J. Chem.

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Thienopyrimidine amide derivatives are important class of organic compounds and show wide range of biological activity. Hence the researchers are paying more attention towards the synthesis of these compounds. A series of thienopyrimidine amide derivatives (13a-m) were synthesized. The newly synthesized amide derivatives (13a-m) were characterized by 1 H NMR, 13C NMR, Mass and IR spectral data. Further these compounds were also evaluated for their antibacterial activity.

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A novel and efficient synthesis of pyrazolo[3,4-d]pyrimidine derivatives and the study of their anti-bacterial activity

Cited by 52 publications

References 18 publications

Ninhydrin in synthesis of heterocyclic compounds

Ninhydrin in synthesis of heterocyclic compounds

Synthesis of heterocycles and fused heterocycles catalyzed by nanomaterials

Synthesis and Antibacterial Activity of Thienopyrimidine Amide Derivatives

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