A Novel Amino Acid Deletion and Substitution inamrBGene Associated with Gentamicin Susceptibility inBurkholderia pseudomalleifrom Malaysian Borneo
Ainulkhir Hussin,
Sheila Nathan,
Muhammad Ashraf Shahidan
et al.
Abstract:Burkholderia pseudomalleiis a highly pathogenic saprophyte that is intrinsically resistant to a wide variety of antibiotics. Resistance to gentamicin is considered as an earmark ofB. pseudomallei. However, rare susceptible strains have been isolated in certain regions due to gene mutations. Currently, data on the susceptible strains’ prevalence and the actual causal mutations are still scarce, particularly in Malaysian Borneo. A pool ofB. pseudomalleiisolates (n= 46) were screened for gentamicin susceptibility… Show more
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