A novel aldo–keto reductase gene is involved in 6′-deoxychalcone biosynthesis in dahlia (Dahlia variabilis)

Abstract

Main conclusion:A novel gene belonging to the aldo-keto reductase 13 family is involved in isoliquiritigenin biosynthesis in dahlia.

All roads lead to Rome: alternative biosynthetic routes in plant specialised metabolism

“…As with many specialised metabolic pathways (Lou et al, 2022), PKS genes are thought to have arisen from the duplication of a gene from a primary metabolic pathway (fatty acid biosynthesis), followed by neofunctionalisation (Austin & Noel, 2003;Naake et al, 2021) Metabolites synthesised through PKS activity rarely accumulate in planta and are usually processed by diverse tailoring enzymes, of which PKRs are one class, increasing polyketide chemical and functional diversity. Few PKRs have been characterised, notably chalcone reductase (Bomati et al, 2005), but new activities have recently been reported from both bryophytes (T-T. Zhu et al, 2023) and angiosperms (Ohno et al, 2022;L. Zhu et al, 2022).…”

“…Few PKRs have been characterised, notably chalcone reductase (Bomati et al ., 2005 ), but new activities have recently been reported from both bryophytes (T‐T. Zhu et al ., 2023 ) and angiosperms (Ohno et al ., 2022 ; L. Zhu et al ., 2022 ). PKSs play a crucial role in guiding the metabolic flux during the PKS reaction, stabilising the intermediates formed and preventing them from undergoing nonspecific cyclisation.…”