A novel 99mTc delivery system using (n,γ)99Mo adsorbed on a large alumina column in tandem with Dowex-1 and AgCl columns

Chattopadhyay, Sankha; Das, Manab Kumar; Sarkar, Suman; Saraswathy, P.; Ramamoorthy, N.

doi:10.1016/s0969-8043(02)00080-5

Cited by 24 publications

(10 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[1,2] In particular, the use of 188 Re liquid-filled balloons for intra-arterial radiation therapy in cardiac patients who have undergone balloon angioplasty is one of the earliest applications for 188 Re. [1,2] In particular, the use of 188 Re liquid-filled balloons for intra-arterial radiation therapy in cardiac patients who have undergone balloon angioplasty is one of the earliest applications for 188 Re.…”

Section: Introductionmentioning

confidence: 99%

“…[1b,1c] For clinical purposes, 188 Re is prepared from 188 W/ 188 Re alumina-based generator systems immediately prior to use, and it is available in the generator eluate as the oxido anion ReO 4 -. [2] The principle of PEC is based on the selective retention of perrhenate on a tiny anion exchange column and subsequent recovery from a small volume of suitable eluent. The solution is eluted from the generator column filled with alumina, on which an acidic solution of Na 2 188 WO 4 (t 1/2 = 69.4 d) is adsorbed (pH = 2-3).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cavity Effect on Perrhenate Recognition by Polyammonium Cages

et al. 2012

View full text Add to dashboard Cite

The affinity of azacryptands towards perrhenate has been investigated by potentiometric, 1 H NMR spectroscopic and ITC studies in aqueous solutions. The association constants could only be determined for the p-xylyl and m-xylyl azacryptands in the hexaprotonated form. The experimental results showed the outstanding affinity of the p-xylyl cryptand for perrhenate, attributable to the geometric complementarity between the anion and the cavity of the receptor. Single crystals of the inclusion complex could also be obtained. The Xray diffraction studies indicate that the perrhenate anion is included in the cavity of the receptor and interacts with the [a]

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cavity Effect on Perrhenate Recognition by Polyammonium Cages

et al. 2012

View full text Add to dashboard Cite

show abstract

“…The idea was based on the work of Moore et al [13] and of Boyd [14,15]. The procedure was adapted from our earlier work on post-elution concentration of pertechnetate [5,6,16].…”

Section: Discussionmentioning

confidence: 99%

“…There is a need for a relatively more user-friendly, reliable, column-type generator system for use in hospitals, which uses (n,g) 99 Mo. We have previously reported the preparation of a jumbo alumina column generator using (n,g) 99 Mo and concentration of a large volume 99m Tc eluate by using weak and strong anion exchanger columns [5,6].…”

Section: Introductionmentioning

confidence: 99%

High radioactive concentration of 99mTc from a zirconium [99Mo]molybdate gel generator using an acidic alumina column for purification and concentration

Sarkar¹,

Saraswathy²,

Arjun³

et al. 2004

Nuclear Medicine Communications

View full text Add to dashboard Cite

About a 4-fold increase in radioactive concentration of Tc was obtained (cf. approximately 10-12 ml normal saline is required for the elution of Tc from the gel column). Generators containing up to 22.2 GBq (600 mCi) Mo in 6-7 g ZrMo gel column (35 x 13 mm) were prepared and a radioactive concentration of Tc up to 4 GBq x ml (110 mCi x ml) was obtained on the first day of use. The overall recovery of Tc was >90%, Mo breakthrough was 10 to 10% and the duration of concentration was 3-5 min. The chemical impurity in terms of Al, Mo and Zr was <10 ppm each. The same procedure for the concentration of pertechnetate was applied to generators with 12-15 g ZrMo gel beds to obtain a higher capacity Tc gel generator, with similar findings.

show abstract

“…The method of AgCl preparation used by Chattopadhyay et al (2002) was used with some modifications. 3 g of AgNO 3 was dissolved in 10 mL of distilled H 2 O.…”

Section: Preparation and Characterization Of Agclmentioning

confidence: 99%