1939
DOI: 10.1001/jama.1939.62800230005012d
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A Note on the Use of Vitamin B6 in Human Nutrition

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1940
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Cited by 54 publications
(3 citation statements)
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“…A more specific effect in nutritionally deficient persons was reported by Spies, Bean, and Ashe (19) who gave pyridoxine to patients previously treated with other members of the vitamin B-complex but who still had symptoms of weakness, insomnia, nervousness, irritability and difficulty in walking. These symptoms were alleviated immediately by pyridoxine.…”
mentioning
confidence: 87%
“…A more specific effect in nutritionally deficient persons was reported by Spies, Bean, and Ashe (19) who gave pyridoxine to patients previously treated with other members of the vitamin B-complex but who still had symptoms of weakness, insomnia, nervousness, irritability and difficulty in walking. These symptoms were alleviated immediately by pyridoxine.…”
mentioning
confidence: 87%
“…Siegel et al (1943) Rabinowitz and Snell (1948) reported whole egg to contain 5. No vitamin B 6 deficiency diseases of humans similar to those of dogs, pigs, or chickens have been recognized, but certain symptoms of pellagra not relieved by thiamine, riboflavin, and niacin have been cured by the administration of pyridoxine hydrochloride (Spies et al, 1939). Vitamin B 6 has been found to play a part in protein metabolism, particularly the conversion of protein to fat (McHenry and Gavin, 1941).…”
mentioning
confidence: 99%
“…Clinical studies have not been very extensive. Spies and his collaborators (10) have noted that certain residual symptoms (i.e., insomnia, irritability, weakness, difficulty in walking and abdominal pain) in treated pellagrins responded to pyridoxine therapy. In a case of arsenical neuritis, Vilter (11) commented on the rapid remission when pyridoxine was added to the already instituted therapy.…”
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confidence: 99%