A Note on the Use of Anticoagulant Therapy in Chronic Brain Syndrome

Abstract

A “single‐blind” study on the use of anticoagulant therapy in 8 geriatric patients with chronic brain syndrome indicated that the subjects performed significantly less well on the Graham‐Kendall test (for organic abnormalities) both immediately after, and three months after cessation of a 4‐month course of treatment. Scores from the Mental Status Questionnaire indicated a significant improvement in psychological functioning after treatment. However, the apparent contradiction in these results could be attributed to differences in the maintenance of positive effects engendered by the initial high levels of motivation. Our findings plus those of Walsh and Rosenberg suggest that a carefully controlled study involving more patients and more varied measuring techniques would add useful information to the understanding of chronic brain syndrome.