A normative modeling approach to quantify white matter changes and predict functional outcomes in stroke patients
Houming Su,
Su Yan,
Hongquan Zhu
et al.
Abstract:ObjectivesThe diverse nature of stroke necessitates individualized assessment, presenting challenges to case-control neuroimaging studies. The normative model, measuring deviations from a normal distribution, provides a solution. We aim to evaluate stroke-induced white matter microstructural abnormalities at group and individual levels and identify potential prognostic biomarkers.MethodsForty-six basal ganglia stroke patients and 46 healthy controls were recruited. Diffusion-weighted imaging and clinical asses… Show more
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