A Noninvasive Oral Neutrophil Assay To Monitor Engraftment, Neutrophil Function and Susceptibility to Infection Following Bone Marrow Transplantation (BMT) in Children and Adolescents.
Abstract:BACKGROUND: A major problem in the post-BMT setting is the determination of neutrophil levels and function that are protective against life threatening infections. Conventional definitions of engraftment by circulating neutrophil counts are unreliable. Identifying successful engraftment of protective neutrophils earlier may negate the need for invasive marrow testing and help predict which patients need empirical antibacterial or antifungal therapy. Monitoring the timing of tissue delivery of neutrophils may s… Show more
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