Background: Frailty syndrome is a pathological, reversible aging process where frailty and comorbidity have a bidirectional relationship. It is characterized by having three of more of the following components: weight loss, exhaustion, slowness, low activity level, and weakness. Methods: We searched PubMed from January 1, 2018 to November 1, 2023. The dates of publication, language of publication, methodological characteristics and the key findings were analyzed separately. Results: We found 550 unfinished studies on the use of diagnostic methods for the Frailty syndrome. Only 26 suitable articles were found. 19 randomised controlled trials, 2 cohort study, 2 cross-sectional study, 1 case study,1 longitudinal study, 1 report. Conclusion: We conducted this evaluation review in order to identify clinical examples of the use of diagnostic methods of fragility syndrome in the period from 2018 to 2023. Only 26 suitable articles were found. This suggests that this topic has been little studied. There is not enough evidence. It is necessary to conduct more original research on this topic.