A Non-Enzymatic Sensor Based on Fc-CHIT/CNT@Cu Nanohybrids for Electrochemical Detection of Glucose

Wang, Fang; Hu, Sheng; Shi, Fengna; Huang, Kexin; Li, Jiarui

doi:10.3390/polym12102419

Cited by 12 publications

(3 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The other goal is to confer special properties to the depolymerized nanostructures [ 5 ], which is more challenging. By using functionalized CNTs as a supporting material, Wang et al [ 114 ] uniformly deposited Cu NPs on acidizing CNTs to form a composite structure of ferrocene–chitosan/CNT@Cu (Fc–CHIT/CNT@Cu) for the electrochemical glucose detection. Given the huge surface area of CNTs, the excellent electrical conductivity of Cu NPs, and the specific synergies of Fc, the electrode showed excellent glucose detection performance.…”

Section: Recent Developments In Cnt-based Nonenzymatic Glucose Sensorsmentioning

confidence: 99%

Carbon nanotubes: a powerful bridge for conductivity and flexibility in electrochemical glucose sensors

Yuwen,

Shu,

Zou

et al. 2023

J Nanobiotechnol

View full text Add to dashboard Cite

The utilization of nanomaterials in the biosensor field has garnered substantial attention in recent years. Initially, the emphasis was on enhancing the sensor current rather than material interactions. However, carbon nanotubes (CNTs) have gained prominence in glucose sensors due to their high aspect ratio, remarkable chemical stability, and notable optical and electronic attributes. The diverse nanostructures and metal surface designs of CNTs, coupled with their exceptional physical and chemical properties, have led to diverse applications in electrochemical glucose sensor research. Substantial progress has been achieved, particularly in constructing flexible interfaces based on CNTs. This review focuses on CNT-based sensor design, manufacturing advancements, material synergy effects, and minimally invasive/noninvasive glucose monitoring devices. The review also discusses the trend toward simultaneous detection of multiple markers in glucose sensors and the pivotal role played by CNTs in this trend. Furthermore, the latest applications of CNTs in electrochemical glucose sensors are explored, accompanied by an overview of the current status, challenges, and future prospects of CNT-based sensors and their potential applications.

show abstract

Section: Recent Developments In Cnt-based Nonenzymatic Glucose Sensorsmentioning

confidence: 99%

Carbon nanotubes: a powerful bridge for conductivity and flexibility in electrochemical glucose sensors

Yuwen,

Shu,

Zou

et al. 2023

J Nanobiotechnol

View full text Add to dashboard Cite

show abstract

“…Tus, attempts have been made to achieve efective GOx immobilization by the introduction of an electrode matrix. Several materials have been explored for the efcient loading of the GOx, including carbon nanotubes (CNTs), polyaniline, graphene, and metal nanoparticles [5][6][7][8]. Among these, CNTs show great potential for enzyme loading due to their large surface area.…”

Section: Introductionmentioning

confidence: 99%

A SiO2 Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose

Mei

Yang

et al. 2023

International Journal of Analytical Chemistry

View full text Add to dashboard Cite

A novel enzyme-based biosensor for glucose detection is successfully developed using layer-by-layer assembly technology. The introduction of commercially available SiO2 was found to be a facile way to improve overall electrochemical stability. After 30 CV cycles, the proposed biosensor could retain 95% of its original current. The biosensor presents good detection stability and reproducibility with the detection concentration range of 1.96 × 10−9 to 7.24 × 10−7 M. This study demonstrated that the hybridization of cheap inorganic nanoparticles was a useful method in preparing high-performance biosensors with a much lower cost.

show abstract

“…[9,15] The sensing capability of an electrocatalyst is affected by its support material. [16,17] In comparison with conductive carbonbased materials such as graphene [18] and carbon nanotubes, [16] boron-doped diamond (BDD) has a wide semiconductor bandgap (E g = 5.47 eV), wide electrochemical window, and excellent stability. Thus, it serves as an ideal electrode material for sensing applications that demand low background currents and high signal-to-noise (S/N) ratios.…”

mentioning

confidence: 99%

Laser‐Engraved Boron‐Doped Diamond for Copper Catalyzed Non‐Enzymatic Glucose Sensing

Gao

Zhang

Zhao

et al. 2022

Adv Materials Inter

View full text Add to dashboard Cite

oxidase has opened up the horizon for continuous glucose monitoring. However, enzymatic glucose sensors showcase slow response, low sensitivity, complex immobilization process, and they are susceptible to temperature, humidity, and pH variations. [5][6][7] Therefore, the development of fabrication methods for high-performance nonenzymatic glucose sensors needs to be explored.In nonenzymatic glucose sensors, catalytic sensing is performed using transition metals immobilized on conductive substrates. [8,9] The role of transition metals is demonstrated in the recently established d-band model, in which the d-band center of the transition metal serves as an electronic descriptor to evaluate the binding strength of the reaction intermediate on the metal. [10,11] When the adsorbate molecule approaches the metal surface, its energy levels are shifted by the metal electrons. Although the wide s-band of the metal only shifts and broadens the electronic state of the molecule, [12] the narrow d-band with large density of states (DOS) splits the electronic state of the molecule into bonding and antibonding states, which determine the chemisorption and desorption processes. As a result, the d-band center can be adopted as a descriptor to evaluate catalytic performance. [13,14] Among all transition metals, Cu is one of the most widely utilized transition metal catalysts, offering great potential as an ideal electrocatalyst for glucose oxidation. [9,15] The sensing capability of an electrocatalyst is affected by its support material. [16,17] In comparison with conductive carbonbased materials such as graphene [18] and carbon nanotubes, [16] boron-doped diamond (BDD) has a wide semiconductor bandgap (E g = 5.47 eV), wide electrochemical window, and excellent stability. Thus, it serves as an ideal electrode material for sensing applications that demand low background currents and high signal-to-noise (S/N) ratios. [19,20] For instance, Pinar et al. [21] achieved the simultaneous detection of epinephrine and lidocaine using a BDD electrode by taking advantage of its wide electrochemical window. The high S/N ratio of BDD electrodes enables electrophysiological recording, dopamine sensing, [22] and real-time drug tracking. [23] However, because BDD is electrochemically inert and has poor glucose sensitivity, decorating BDD electrodes with transition metals may offer a unique opportunity for the development of glucose sensors with ultrahigh sensitivity and improved stability. Robust and high-performance electrochemical electrodes for non-enzymatic glucose sensing are in constant demand. Herein, a hierarchical nonenzymatic glucose sensing electrode on boron-doped diamond (BDD) is fabricated using high-speed laser engraving and pulsed electrodeposition of Cu nanostructures. The obtained electrode contains a densely packed Cu nanoflake (CuNF) array periodically decorated on the laser-engraved BDD. The hierarchical nanoarchitecture combines the d-band catalytic activity of the CuNFs with the low capacitive background current of the engra...

show abstract

A Non-Enzymatic Sensor Based on Fc-CHIT/CNT@Cu Nanohybrids for Electrochemical Detection of Glucose

Cited by 12 publications

References 48 publications

Carbon nanotubes: a powerful bridge for conductivity and flexibility in electrochemical glucose sensors

Carbon nanotubes: a powerful bridge for conductivity and flexibility in electrochemical glucose sensors

A SiO2 Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose

Laser‐Engraved Boron‐Doped Diamond for Copper Catalyzed Non‐Enzymatic Glucose Sensing

Contact Info

Product

Resources

About