A nomogram model based on the combination of the systemic immune-inflammation index and prognostic nutritional index predicts weight regain after laparoscopic sleeve gastrectomy

Zhao, Jie; Jiang, Yicheng; Qian, Jun; Qian, Zhifen; Yang, Haojun; Shi, Weihai; Gong, Yubin; Jiao, Yuwen; Tang, Liming

doi:10.1016/j.soard.2022.07.014

Cited by 5 publications

(3 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The average age of patients included in this study was 29.7 ± 7.6 years old, which is similar to the average age of patients studied in other Chinese centers [38,39]. Meanwhile, in the classic study of The SLEEVEPASS Randomized Clinical Trial in a Western center, the average age of patients underwent LSG was 48.5 ± 9.6 years old [2,3,4].…”

Section: Discussionsupporting

confidence: 71%

Fat mass index predicts the effect of weight loss and quality of life early after laparoscopic sleeve gastrectomy

Jiang,

Zhong,

Shang-Guan

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Fat mass index (FMI) is a body composition indicator that reflects body fat content. Laparoscopic sleeve gastrectomy (LSG) is widely performed in patients with obesity. Objective This study aimed to evaluated the value of the FMI in predicting weight loss effect and quality of life early after LSG. Material and Methods From January 2014 to July 2022, the clinical data and computed tomography (CT) images of patients underwent LSG at a tertiary referral teaching hospital were analyzed. Body composition indicators were calculated using the SliceOmatic software. Achieving initial body mass index within 6 months postoperatively was defined as early eligible weight loss (EEWL). The relationship between body composition and EEWL was analyzed. Results A total of 243 patients were included. Receiver operating characteristic (ROC) curve analysis showed that the predictive value of the FMI for EEWL in patients after LSG was higher than that of other indicators (all P<0.05; area under the curve = 0.813). The best FMI cut-off point was 13.662. Accordingly, the patients were divided into the high-FMI group and low-FMI group. The %EWL and BMI of patients in the low-FMI group at 1, 3, 6, 9, 12 and 24 months after surgery were better than those in the high-FMI group (all P<0.001). Patients in the low-FMI group had higher BAROS (Bariatric Analysis and Reporting Outcome System) scores than those in the high-FMI group (P<0.001). Conclusion Compared with other body composition indicators, FMI can effectively predict the early effect of weight loss and quality of life after LSG.

show abstract

Section: Discussionsupporting

confidence: 71%

Fat mass index predicts the effect of weight loss and quality of life early after laparoscopic sleeve gastrectomy

Jiang,

Zhong,

Shang-Guan

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Furthermore, no statistical significance was found between the two indicators upon readmission. Although PNI and CONUT were proposed in previous studies for nutritional assessment (21)(22)(23), the differences in target populations, types of surgeries, and focus on readmission might have caused differences in these study findings. Therefore, there is a need for more sensitive and specific indicators in the assessment of nutritional status and prognosis in obese patients.…”

Section: Discussionmentioning

confidence: 89%

Baseline 25(OH)D level is a prognostic indicator for bariatric surgery readmission: a matched retrospective cohort study

Shang,

Chen,

Wang

et al. 2024

Front. Nutr.

View full text Add to dashboard Cite

IntroductionManaging postsurgical complications is crucial in optimizing the outcomes of bariatric surgery, for which preoperative nutritional assessment is essential. In this study, we aimed to evaluate and validate the efficacy of vitamin D levels as an immunonutritional biomarker for bariatric surgery prognosis.MethodsThis matched retrospective cohort study included adult patients who underwent bariatric surgery at a tertiary medical center in China between July 2021 and June 2022. Patients with insufficient and sufficient 25(OH)D (< 30 ng/mL) were matched in a 1:1 ratio. Follow-up records of readmission at 3 months, 6 months, and 1 year were obtained to identify prognostic indicators.ResultsA matched cohort of 452 patients with a mean age of 37.14 ± 9.25 years and involving 69.47% females was enrolled. Among them, 94.25 and 5.75% underwent sleeve gastrectomy and gastric bypass, respectively. Overall, 25 patients (5.54%) were readmitted during the 1-year follow-up. The prognostic nutritional index and controlling nutritional status scores calculated from inflammatory factors did not efficiently detect malnourishment. A low 25(OH)D level (3.58 [95% CI, 1.16–11.03]) and surgery season in summer or autumn (2.68 [95% CI, 1.05–6.83]) increased the risk of 1-year readmission in both the training and validation cohorts. The area under the receiver operating characteristic curve was 0.747 (95% CI, 0.640–0.855), with a positive clinical benefit in the decision curve analyses. The relationship between 25(OH)D and 6-month readmission was U-shaped.ConclusionSerum 25(OH)D levels have prognostic significance in bariatric surgery readmission. Hence, preferable 25(OH)D levels are recommended for patients undergoing bariatric surgery.

show abstract

“…Interestingly, we also found that HSI was positively correlated with circulating Prdx1 (r=0.383, p =0.002). Several studies have observed increased inflammatory proteins, such as C-reactive protein, which declined after bariatric surgery in T2DM patients with obesity ( 53 ).…”

Section: Discussionmentioning

confidence: 99%

Preoperative circulating peroxiredoxin 1 levels as a predictor of non-alcoholic fatty liver disease remission after laparoscopic bariatric surgery

Cheng

Xie

et al. 2022

Front. Endocrinol.

View full text Add to dashboard Cite

BackgroundNon-alcoholic fatty liver disease (NAFLD) is associated with obesity and insulin resistance and can be improved after bariatric surgery. Circulating Peroxiredoxin 1 (Prdx1) protein was reported to regulate energy metabolism and inflammation. This study aimed to investigate the roles of serum prdx1 in NAFLD patients with obesity undergoing LSG and to develop a prognostic model to predict the remission of severe NAFLD.MethodsThe data of 93 participants from a tertiary hospital were assessed. Before laparoscopic sleeve gastrectomy (LSG) and three months after LSG, anthropometric parameters, laboratory biochemical data, and abdominal B-ultrasound results were collected, and their hepatic steatosis index (HSI) and triglyceride-glucose index (TyG) were calculated. A NAFLD improvement (NAFLD-I) nomogram prediction model was constructed using the least absolute shrinkage and selection operator (LASSO) regression and multiple regression, and its predictive ability was verified in a validation cohort.ResultsThe baseline Prdx1 (OR: 0.887, 95% CI: 0.816-0.963, p=0.004), preoperative TyG (OR: 8.207, 95% CI: 1.903-35.394, p=0.005) and HSI (OR: 0.861, 95% CI: 0.765-0.969, p=0.013) levels were independently associated with NAFLD-I at three months after LSG in NAFLD patients with obesity. In the primary and validation cohorts, the area under the receiver operating characteristic (AUC) of the developed nomogram model was 0.891 and 0.878, respectively. The preoperative circulating Prdx1 levels of NAFLD patients with obesity were significantly reduced after LSG (25.32 [18.99-30.88] vs. 23.34 [15.86-26.42], p=0.001). Prdx1 was related to obesity and hepatic steatosis based on correlation analysis.ConclusionThe nomogram based on preoperative serum prdx1, HSI and TyG could be an effective tool for predicting remission of severe NAFLD after LSG.

show abstract

A nomogram model based on the combination of the systemic immune-inflammation index and prognostic nutritional index predicts weight regain after laparoscopic sleeve gastrectomy

Cited by 5 publications

References 35 publications

Fat mass index predicts the effect of weight loss and quality of life early after laparoscopic sleeve gastrectomy

Fat mass index predicts the effect of weight loss and quality of life early after laparoscopic sleeve gastrectomy

Baseline 25(OH)D level is a prognostic indicator for bariatric surgery readmission: a matched retrospective cohort study

Preoperative circulating peroxiredoxin 1 levels as a predictor of non-alcoholic fatty liver disease remission after laparoscopic bariatric surgery

Contact Info

Product

Resources

About