A NIR-mediated MXene@CuS composite for eliminating osteosarcoma and promoting osteogenesis

Zhang, Xiaoying; Liu, Peixin; Lu, Ying; Zhang, Jingying; Han, Jiali; Zhang, Guannan; Song, Jianbo

doi:10.1016/j.matlet.2023.133912

Cited by 3 publications

(2 citation statements)

References 6 publications

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Section: Ms-based Mxene Nanocomposites: Properties and Applicationmentioning

confidence: 99%

“…To be effective in the treatment of cancer, MXene-based NPs with unique features and high stability are desirable. The addition of MSs such CuS, PbS, CdS, AgS 2 and MoS 2 to MXenes generates electron-transfer capability, 204 which with the addition of high NIR absorption capability makes 2D MS NPs highly desirable NMs in cancer diagnosis and treatment. 205,206 Properly designed MS-based MXene composites have been reported to exhibit low biological toxicity, high photoelectric conversion efficiency, high sensitivity, and stable biosensing with a suitable band gap, all characteristics that are favored for cancer treatment NPs.…”

Section: Nomentioning

confidence: 99%

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Review of Metal Sulfide-Based MXene Nanocomposites for Environmental Applications, Gas Sensing, Energy Storage, and Photothermal Therapy

Fard,

Raeisi,

Yousefipour

et al. 2024

ACS Appl. Nano Mater.

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Application of nanoparticles (NPs) guides the design of the particle for enhancing specific properties of interest for that particular application. Two-dimensional transition-metal carbides, nitrides, and carbonitrides [also known as MXene nanosheets (NSs)] have attracted interest as an approach for improving the properties of functional materials of NPs. The modification of surface chemistry has frequently been employed to amplify favorable physical and chemical characteristics of MXenes. A straightforward, economical, and remarkably effective technique in this aspect is the implementation of metal sulfide (MS) nanostructures that adhere to MXene NSs through van der Waals interactions. The inherent self-assembly properties of these structures enable simple regulation of the packaging density of the particles. For environmental remediation, properties such as narrow band gap and increased electron and hole transfer make MS/MXene nanocomposites suitable for the degradation and removal of pollutants. For energy applications, the MXene NSs serve as conductive substrates, facilitating fast electron and ion transport, to prevent the aggregation of MS nanostructures. Transition-metal sulfides act as spacers in these designs. In the field of medicine, MS/MXene nanocomposites can be utilized for targeted therapy, for the diagnosis and treatment of cancer, and as antibacterial agents due to their high absorption in the near-infrared region. The present review summarizes the integration of MS/MXene nanocomposites, with a brief discussion of the synthesis and traits of MXenes, along with the progress of various MXene composites, applications of the various NSs, and some of the challenges and future prospects associated with the development of MS/MXene nanocomposites, while highlighting their potential for diverse applications.

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Section: Ms-based Mxene Nanocomposites: Properties and Applicationmentioning

confidence: 99%

Section: Nomentioning

confidence: 99%

Review of Metal Sulfide-Based MXene Nanocomposites for Environmental Applications, Gas Sensing, Energy Storage, and Photothermal Therapy

Fard,

Raeisi,

Yousefipour

et al. 2024

ACS Appl. Nano Mater.

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Hemostatic nanofibers/chitosan composite aerogel for potential chemo-photothermal therapy

Fu,

Li,

Chen

et al. 2025

Journal of Molecular Structure

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MXene-reinforced bioactive polymer hydrogels for biomedical applications

Gu,

Chen,

Wei

et al. 2024

APL Materials

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MXenes, a novel class of two-dimensional (2D) materials, have attracted considerable attention in various fields, especially in drug delivery, wound healing, bone tissue engineering, biosensing, and cancer treatment. Thanks to their remarkable physicochemical properties, MXenes hold great promise for biomedical applications. Concurrently, hydrogels composed of polymers have been extensively utilized in biomedical contexts. The unique properties of MXenes facilitate their integration into various bioactive hydrogels with enhanced functions and properties, thereby endowing the composites with multifunctional capabilities. MXene-reinforced polymer hydrogels (MRPHs) synergistically combine the advantageous characteristics of both MXenes and hydrogels, making them highly adaptable for integration with other theranostic strategies in medical applications. In this comprehensive review, we demonstrate recent advances in the design and synthesis of MRPHs for biomedical applications. Specifically, we introduce the unique functions and properties of MRPHs and analyze the methods for tailoring the functions of MRPHs by incorporating them with other active components, including functional molecules, 2D materials, metal ions, natural polymers, and drugs/genes. We then discuss the biomedical applications of the designed bioactive MRPHs in wound healing, tissue engineering, biosensors, and cancer therapy. We hope that this work provides valuable guidance and inspiration for readers to develop novel MRPHs for advanced applications.

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A NIR-mediated MXene@CuS composite for eliminating osteosarcoma and promoting osteogenesis

Cited by 3 publications

References 6 publications

Review of Metal Sulfide-Based MXene Nanocomposites for Environmental Applications, Gas Sensing, Energy Storage, and Photothermal Therapy

Review of Metal Sulfide-Based MXene Nanocomposites for Environmental Applications, Gas Sensing, Energy Storage, and Photothermal Therapy

Hemostatic nanofibers/chitosan composite aerogel for potential chemo-photothermal therapy

MXene-reinforced bioactive polymer hydrogels for biomedical applications

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