A newly modified 595-nm pulsed dye laser with compression handpiece for the treatment of photodamaged skin

Abstract

This novel 595-nm pulsed dye laser, with a modified pulse sequence and CHP, now has the versatility to safely treat both pigment and vascular changes associated with photoaging.

Rosacea treatment using the new‐generation, high‐energy, 595 nm, long pulse‐duration pulsed‐dye laser

“…However, previous studies have shown improvement in enlarged pores and rhytides following PDL treatment [6,[19][20][21][22][23][24]. Although laser treatment of unwanted vasculature works by targeting unwanted vessels directly, perhaps with the added benefit of an inflammatory response post-treatment; the ability of laser treatment at the 595 nm wavelength to improve fine lines and texture as well as to shrink enlarged pores, probably depends upon a number of intermediate steps involving activation of mast cells and other inflammatory cells, which in turn impart their influence by remodeling sun-damaged extracellular matrix in the dermis.…”

Long‐pulsed dye laser versus intense pulsed light for photodamaged skin: A randomized split‐face trial with blinded response evaluation

“…Today many non-ablative devices are used with cooling techniques in order to minimize treatment-related pain and to diminish unspecific thermal damage and thereby, to reduce the risk of inducing adverse effects [20,[23][24][25]. In our study the LPDL was equipped with an integrated DCD whereas the IPL system did not use cooling, thus explaining the significantly higher pain scores on the IPL-treated sides compared to the LPDL treated sides.…”

“…of higher fluences [20]. Moreover, the use of a compression handpiece with the LPDL, which removes blood from the treatment area, thereby eliminating hemoglobin as a competing chromophore, explains the effectiveness of LPDL and the comparable results of LPDL to broadband IPL for the treatment of pigmented lesions.…”

“…Non-ablative rejuvenation with LPDL and IPL is widely used to clear telangiectasias and irregular pigmentation and to improve skin-texture [4][5][6][7][8]20,22]. Randomized and non-RCTs have previously evaluated the efficacy of PDL and IPL rejuvenation showing significant improvements of telangiectasias and irregular pigmentation in up to 89% and 77% of patients, respectively, a couple of months after 2-3 IPL or PDL treatments [4,7,8].…”

“…LPDL and IPL systems target the endogenous chromophores haemoglobin and melanin, which results in vessel clearance and reduction of dyschromia due to the concept of selective photothermolysis [4,7,8,17,19,20]. The efficacy of PDL and IPL for the treatment of sundamaged skin has previously been documented in controlled trials, showing substantial efficacy on vessel clearance and reduction of pigmentation [4][5][6][7][8][9][10][11].…”