A newly isolated strain of Haematococcus pluvialis JNU35 improves the growth, antioxidation, immunity and liver function of golden pompano ( Trachinotus ovatus )

Abstract

The green alga Haematococcus pluvialis JNU35 is enriched in astaxanthin, linoleic acid and linolenic acid. H. pluvialis JNU35 can be used as an immunostimulant in aquatic feed. Here, the role of H. pluvialis JNU35 in mediating growth, antioxidation, immunity and liver function of Trachinotus ovatus was examined through feeding test. HP0, HP1 and HP5 diets containing 0, 10 and 50 g/kg H. pluvialis JNU35 were prepared for 6-week feeding. It is shown that the supplement of H. pluvialis JNU35 in diet significantly triggers fish growth through elevating activities of digestive enzymes, food intaking, villus length and upregulating growth hormone and insulin-like growth factor. H. pluvialis JNU35 supplementation protected from oxidative stress through the Nrf2-ARE pathway and thus elevated activities of antioxidant enzymes. Meanwhile, H. pluvialis JNU35 supplementation protected liver function by declining lipid deposition, inhibiting hepatocyte apoptosis, upregulating anti-inflammatory cytokines and downregulating pro-inflammatory cytokines. Non-specific immune ability of fish was also promoted by regulating expressions of complement 4, c-type lysozyme and heat shock protein 70 in HP1 and HP5 diets. The blood health state of fish was improved by H. pluvialis JNU35 supplementation. In conclusion, H. pluvialis JNU35 promoted growth, antioxidation, immunity and liver function in T. ovatus.

A Newly Isolated Strain of Haematococcus pluvialis GXU-A23 Improves the Growth Performance, Antioxidant and Anti-Inflammatory Status, Metabolic Capacity and Mid-intestine Morphology of Juvenile Litopenaeus vannamei

“…In the present study, L. vannamei fed with the H. pluvialis GXU-A23 diet obtained the better growth performance (WG and SGR) compared to that of the control group. Similar results also reported in Pseudosciaena crocea ( Li et al, 2014 ) , Trachinotus ovatus ( Zhao et al, 2021 ) , L. vannamei (initial weight: ∼ 1.0 g) ( Ju et al, 2012 ). H. pluvialis GXU-A23 contains astaxanthin with 3S-3′S type which is the same structure in Salmo salar and other aquatic animals ( Higuera-Ciapara et al, 2006 ).…”

“…Apart from that, the H. pluvialis showed the better astaxanthin accumulation property in the urea as nitrogen source than NaNO 3 and NH 4 HCO 3 ( Wang et al, 2019 ). In our previous study, the two-step batch culture strategy was used to successfully culture H. pluvialis JNU35, which contained 31.70 g/kg astaxanthin ( Zhao et al, 2021 ). Since astaxanthin was mostly produced by nature H. pluvialis , the newly strain of H. pluvialis GXU-A23 could remarkably improve the production industry of astaxanthin as well as reduce the product budget.…”

Effects of Dietary Sodium Acetate on Growth Performance, Fillet Quality, Plasma Biochemistry, and Immune Function of Juvenile Golden Pompano (Trachinotus ovatus)

“…Golden pompano, Trachinotus ovatus is an economically important fish species because of its advantages of growth, flesh quality, and salinity tolerance [15]. Unfortunately, golden pompano often suffered from inflammation and disease due to intensive culture pattern [16]. SA supplementation might provide a new idea to relieve these symptoms of T. ovatus after the antibiotics were banned.…”

Microalgae Derived Astaxanthin: Research and Consumer Trends and Industrial Use as Food

“…Further studies assessing the antimicrobial and antiviral activity of astaxanthin are necessary as the amount of data currently available in the literature are limited. Other health-promoting properties of astaxanthin reported in the literature, assessed using animal models, include: the preservation of visual function and the protection of retinal ganglion cells apoptosis after ischemic results [90], the promotion of growth and liver function [91], benefits on skin health [92], and anti-apoptotic activity [67].…”