For a weakly nonholonomic system, the Lie symmetry and approximate Hojman conserved quantity of Appell equations are studied. Based on the Appell equations for a weakly nonholonomic system under special infinitesimal transformations of a group in which the time is invariable, the definition of the Lie symmetry of the weakly nonholonomic system and its first-degree approximate holonomic system are given. With the aid of the structure equation that the gauge function satisfies, the exact and approximate Hojman conserved quantities deduced directly from the Lie symmetry are derived. Finally, an example is given to study the exact and approximate Hojman conserved quantity of the system.