A New Toxicant Occurring Naturally in Certain Samples of Plant Foodstuffs

Franke, Kurt W.; Tully, W. C.

doi:10.3382/ps.0150316

Cited by 19 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Franke and Tully (1936) reported the production of deformed chick embryos in eggs from hens fed a diet which contained a toxic principle. Methylseleninic acid appears to be even more toxic than selenite or selenate.…”

Section: Resultsmentioning

confidence: 99%

Toxicity of Various Selenium Derivatives to Chick Embryos

1973

View full text Add to dashboard Cite

Several selenium derivatives were injected into 4-day old chick embryos and their LD 50 values were calculated. A recently identified excretory product from rats was shown to be low in toxicity to chick embryos. The most toxic compound in the series studied was methylseleninic acid. Embryonic monstrosities were produced in this study especially by the injection of sodium selenite or selenomethionine. The data are discussed with respect to how they agree with the pathway of selenium reduction proposed for molds.

show abstract

Section: Resultsmentioning

confidence: 99%

Toxicity of Various Selenium Derivatives to Chick Embryos

1973

View full text Add to dashboard Cite

show abstract

Selenium Toxicity in Domestic Animals

Giri

Ranjan

Bharti

2021

Selenium Contamination in Water

View full text Add to dashboard Cite

Monstrosities produced by the injection of selenium salts into hens' eggs

Franke¹,

Moxon²,

Poley³

et al. 1936

Anat. Rec.

View full text Add to dashboard Cite

Chick monsters were consistently produced in eggs from localities where low hatchability had been observed and where toxic foodstuffs were produced (Franke and Tully, '35). I n order to prove that the foodstuff, and not the quality of the stock, was the causative factor, chicks of known stock were fed toxic grain produced in the localities where low hatchability and toxic foodstuffs are common (Tully and Franke, '35 ; Franke and Tully, '36). Following the clue provided by Robinson ( '33) who demonstrated the presence of selenium in a sample of toxic wheat, selenium salts were injected into normal eggs, thereby proving that selenium was the causative agent in the production of monsters.The methods employed were as follows : Eggs were candled to outline the air cells. The area over the air cell was swabbed with an iodine solution, and the selenium solution was injected by puncturing the shell with a hypodermic needle. The punctures were then closed by applying discs of thin paper dipped into egg white.Various concentrations of selenium were used, both in the form of sodium selenite and sodium selenate. I n estimating the concentration, it was assumed that the average egg white plus yolk weighed 50 gm.

show abstract

A New Toxicant Occurring Naturally in Certain Samples of Plant Foodstuffs

Cited by 19 publications

References 2 publications

Toxicity of Various Selenium Derivatives to Chick Embryos

Toxicity of Various Selenium Derivatives to Chick Embryos

Selenium Toxicity in Domestic Animals

Monstrosities produced by the injection of selenium salts into hens' eggs

Contact Info

Product

Resources

About