A New Toxicant Occurring Naturally in Certain Samples of Plant Foodstuffs

Franke, Kurt W.; Potter, Van R.

doi:10.1093/jn/10.2.213

Cited by 52 publications

(16 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lipid peroxidation is a complex pathway in which fatty acyl hydroperoxides form as a free radical chain process reaction between unsaturated fatty acids and reactive oxygen species [79]. Lipid degradation and oxidative rancidity have occurred due to the sequence of secondary reactions resulting from primary autoxidation that cause changes in avour, loss of nutrition quality environmental pollution among others [90]. Over the trial period, organic selenium (ADS18 > Se-Yeast) supplementation decreased the MDA content in egg yolk, breast, and thigh muscle, and blood.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Sodium Selenite, Selenium Yeast, and Bacterial Enriched Protein on Egg Yolk Colour, Antioxidant Profiles and Oxidative Stability

Muhammad

Loh

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: The chicken egg is one of the nature’s flawlessly preserved biological products, recognized as an excellent source of nutrients for humans. Selenium (Se) is an essential micro-element that plays a key role in biological processes. Organic Se sources have shown many advantages over inorganic Se in poultry and can be produced biologically by microbial reduction of Se. Therefore, the possibility of integrating Se enriched bacteria as a supplement in poultry feed can provide an interesting source of organic Se, thereby increase egg Se concentration, improve oxidative stability and offer health-related advantages to humans. The objective of this study was to examine the effects inorganic and different organic Se sources on egg yolk colour, antioxidant profile, oxidative stability, and storage effect in relation to the treatments for fresh and stored egg yolk at 4±2 0C for 14 days. Results: The results reveals that dietary Se supplementation, especially the organic (ADS18 > Se-Yeast) sources influence (p < 0.05) egg yolk colour. Dietary inorganic Se and organic Se were noted to significantly improves egg yolk and breast meat antioxidants profile (total carotenoid and phenol content). There was a significant (p < 0.05) decrease in total cholesterol in fresh, stored egg yolk and breast muscle of Se treated groups compared with control. Whereas for breast muscle, only hens with organic Se supplementation (ADS18 > Se-Yeast) showed lower (p < 0.05) cholesterol compared to inorganic and control hens. The oxidative stability parameters of the eggs, breast and thigh muscle, and plasma showed a significant decrease (p < 0.05) in primary oxidation products (MDA) concentrations with hens supplemented with ADS18. However, the MDA content increased (p < 0.05) with an advanced storage period in egg yolk. It should be noted that, compared to inorganic Se and basal diets, egg yolk from hens fed with organic Se remain fresh for 2 weeks.Conclusions: Dietary Se organic supplementation (ADS18 > Se-Yeast) improves egg yolk colour, antioxidant profile, and oxidative status of egg yolk and tissue. For egg enrichment and antioxidant properties, the source of supplemented organic Se is essential. Thus, ‘’functional eggs’’ enriched with organic selenium becomes possible to produced.

show abstract

Section: Discussionmentioning

confidence: 99%

“…It was allowed for at least 10 min at room temperature before taking the absorbance at 550 nm against a blank (prepared without sample). The cholesterol standards (Sigma L-4646) were per the method of [94], with a concentration of 0, 10,20,30,40,50,60,70,80,90, and 100 µg cholesterol per ml.…”

Section: Data Collection and Chemical Analysismentioning

confidence: 99%

Effect of Sodium Selenite, Selenium Yeast, and Bacterial Enriched Protein on Egg Yolk Colour, Antioxidant Profiles and Oxidative Stability

Muhammad

Loh

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Franke & Pot ter (79) state that the symptoms observed in rats which are fed toxic grains are quite similar to those which follow the ingestion of normal wheat to which sodium selenite is added. In both cases a severe anemia develops in most rats when the selenium content of the diet is 20 to 30 p.p.m.…”

Section: Seleniummentioning

confidence: 93%

Mineral Metabolism

Hart¹,

Elvehjem²

1936

Annu. Rev. Biochem.

View full text Add to dashboard Cite

“…Both diseases were forms of selenosis due to the ingestion of cereal crops, animal forage and Astragalus (or better known as "locoweed") all in which high doses of selenium were found due to the selenium-rich soils. [2][3][4][5] This investigation concluded that selenium "is in a compound very similar to cysteine." 6 However this was not widely recognized as it predated the discovery of selenocysteine by 40 years.…”

Section: Introductionmentioning

confidence: 99%

“…al. reports novel results of their metal-free synthesis of benzimidazole-fused[1,2,4] thiadiazoles from the reaction of 2aminobenzimidazole and isothiocyanates (ITC), isoselenocyanates (ISC) and isocyanates 70.…”

mentioning

confidence: 99%

Isoselenocyanates: Synthesis and Their Use for Preparing Selenium-Based Heterocycles

Neri

Bossmann

2021

Synthesis

View full text Add to dashboard Cite

Isoselenocyanates (ISCs) are a class of organoselenium compounds that have been recognized as potential chemotherapeutic and chemopreventative agents against cancer(s) and infectious disease. ISC compounds are chemically analogous to their isosteric relatives, isothiocyanates (ITCs), however possess increased biological activity, such as an increased cytotoxicity against cancer cells. ISCs not only serve as significant products, but also as precursors and essential intermediates for a variety of organoselenium compounds, such as selenium-containing heterocycles which are biologically active. While the syntheses of ISCs have become less difficult to accomplish, the syntheses of selenium-containing heterocycles have been found often difficult due to the use of highly toxic selenium reagents. Because of this, ISCs can serve as versatile reagents in the preparation of these heterocycles. In this review, the classical and recent syntheses of ISCs will be discussed, along with notable and recent synthetic work in using ISCs to access novel selenium-containing heterocycles.

show abstract

A New Toxicant Occurring Naturally in Certain Samples of Plant Foodstuffs

Cited by 52 publications

References 3 publications

Effect of Sodium Selenite, Selenium Yeast, and Bacterial Enriched Protein on Egg Yolk Colour, Antioxidant Profiles and Oxidative Stability

Effect of Sodium Selenite, Selenium Yeast, and Bacterial Enriched Protein on Egg Yolk Colour, Antioxidant Profiles and Oxidative Stability

Mineral Metabolism

Isoselenocyanates: Synthesis and Their Use for Preparing Selenium-Based Heterocycles

Contact Info

Product

Resources

About