A new therapeutic concept for the treatment of cystic hygroma

Farmand, M; Kuttenberger, Johannes

doi:10.1016/s1079-2104(96)80013-8

Cited by 38 publications

(26 citation statements)

References 19 publications

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“…Many different drugs were used to mimic what may occur spontaneously. The drugs included alcoholic solution of zein (Ethibloc) 10 , acetic acid", fibrin sealant', triamcinolone 13 In 1977 bleomycin, was proposed as a new sclerosing agent for cystic hygroma. 14°' S After that several trials have been reported using bleomycin with good or excellent results in up to 88% of cases.…”

Section: Discussionmentioning

confidence: 99%

Non surgical management of cystic lymphangioma

Rawat

Sinha

Kanojia

et al. 2006

Indian J Otolaryngol Head Neck Surg

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Section: Discussionmentioning

confidence: 99%

Non surgical management of cystic lymphangioma

Rawat

Sinha

Kanojia

et al. 2006

Indian J Otolaryngol Head Neck Surg

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“…11 Also, intravenous cyclophosphamide has been used for treatment of suprahyoid lymphangioma. 12 These modalities have been found to be ineffective and associated with severe complications by some authors, who consider total surgical removal of the lesion to be the treatment of choice.…”

mentioning

confidence: 99%

Total, Subtotal, and Partial Surgical Removal of Cervicofacial Lymphangiomas

Riechelmann

Muehlfay²,

Keck³

et al. 1999

Arch Otolaryngol Head Neck Surg

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Objectives:To compare different surgical interventions for the treatment of extensive cervicofacial lymphangiomas and to define the minimal extent of surgery necessary to control disease.Design: Retrospective study. Mean ± SD follow-up was 31 ± 4 months after surgery. Surgical procedures were grouped as follows: (1) total removal, (2) subtotal removal (all cystic structures removed, small plaques of cyst walls left attached to vital structures), (3) partial removal (major cysts removed, some partially resected cystic structures left in place), and (4) incision and aspiration with subsequent compression bandage. Control of disease was defined as no recurrent or residual tumor or as recurrent or residual tumor less than 10% of initial tumor size without evidence of growth on several postoperative examinations and without clinical symptoms or aesthetic disfigurement.Patients: Twenty-one patients with cervicofacial lymphangiomas (Ͼ3 cm in maximum diameter) without thoracic involvement were evaluated. Fifteen patients were 6 years or younger and 6 were older than 6 years. No surgery was yet performed in 3 patients, for a total of 24 surgical interventions in 18 patients.Setting: Hospitalized care in 2 referral centers.Results: After total removal, disease was controlled in 5 of 5 cases; after subtotal removal, in 8 of 9 cases; after partial removal, in 1 of 7 cases; and after incision and aspiration with subsequent compression bandage, in 0 of 3 cases. Two complications were encountered-1 fully reversible paresis of the marginal branch of the facial nerve and 1 secondary healing.Conclusions: Surgical removal of cervicofacial lymphangiomas is a safe treatment modality. Disease control can be achieved if all cystic structures are removed. Small plaques of cyst walls attached to vital structures may be left in place. If small cystic extensions of lymphangiomas are only opened and left in place or if lymphangiomas are only drained following compression bandage, symptomatic residual tumor or recurrence is frequent.

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“…Complete surgical excision at an early point in time is the treatment of choice [12][13][14]. Surgery should be done with care to avoid leaving islands of tissue to act as foci for recurrence [15], indeed a 20% rate of recurrence has been reported [14].…”

Section: Discussionmentioning

confidence: 99%

“…Other complications include sepsis, infection and fistula formation [17]. In very young children, the blood loss associated with a major procedure and the danger of inflammatory complications could cause serious problems [13]. Other treatment modalities have been reported, such as marsupialization, injection of sclerosing agents, an steroids, diathermy and radiotherapy in unresectable or persistent cases [13,[17][18][19].…”

Section: Discussionmentioning

confidence: 99%

“…In very young children, the blood loss associated with a major procedure and the danger of inflammatory complications could cause serious problems [13]. Other treatment modalities have been reported, such as marsupialization, injection of sclerosing agents, an steroids, diathermy and radiotherapy in unresectable or persistent cases [13,[17][18][19]. Injection of sclerosing agents into the lesion such as OK432 (a lyophilized mixture of group A streptococcus pyogenes of human origin), 50% dextrose, triamcinalone, bleomycin, fibrin sealant and hydrocolloid impression material has had some success.…”

Section: Discussionmentioning

confidence: 99%

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Cystic Hygroma in an Adult; a Case Report

Veeraraghavan¹,

Denny

Ashok

2008

Libyan Journal of Medicine

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Abstract; Lymphangioma is a benign infiltrative malformation of the lymphatic channels. Cystic lymphangioma or cystic hygroma is a subtype of lymphangioma which exhibits large macroscopic cystic space histologically. The cause of cystic hygroma is believed to be developmental defect or primary Multilocular cystic malformation of dilated lymphatic channels. Cystic hygroma is a common and distinct entity that is not manifested in the oral cavity but occurs in the neck as a large, deep diffuse swelling. They are usually found in the posterior triangle of the neck. They often cross the midline, reaching axilla and mediastinum. Such localization verifies the complexity and extent of the lymphatic system in the cervical region when compared to other regions of the body. The five main locations where cystic hygroma can occur are, cervical (75-90%), axillary (20%), inguinal, retroperitoneal and thoracic. They usually appear as solitary lesions. They are usually infiltrative, often separating fascial planes and incorporating nerves, muscles, and blood vessels. They are fluctuant, freely mobile, compressible, painless and transilluminate well. The skin overlying the lesion is normal and usually there is no associated lymphadenopathy. Various treatment modalities have been tried. Surgery has been the main form of treatment, but total removal is not possible in all cases because of the extent of the lesion, which sometimes involves vital structures. We report a case of cystic hygroma in a young male patient.

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A new therapeutic concept for the treatment of cystic hygroma

Cited by 38 publications

References 19 publications

Non surgical management of cystic lymphangioma

Non surgical management of cystic lymphangioma

Total, Subtotal, and Partial Surgical Removal of Cervicofacial Lymphangiomas

Cystic Hygroma in an Adult; a Case Report

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