Purpose: To describe the oncological safety and validity of the modified hybrid operation without intraoperative patient repositioning for upper urinary tract urothelial carcinoma (UTUC) patients. Materials and Methods: We collected and retrospectively analyzed the clinical data of 63 consecutive patients underwent the modified hybrid operation for localized UTUC at The Second Hospital of Tianjin Medical University between July 2018 and July 2019. Details of the modified operating technique were summarized and described. Results: All procedures were successful and no reposition or re-sterilization occurred during these operations. The operative time was 135 mins (IQR:125-145) and estimated blood loss was 35 ml (IQR:30-45.5), the time of distal ureter and bladder cuff resection was only 40 mins (IQR:35-47.5). No positive margins were found by pathological investigation. No complication related to the modified position was detected. Follow-up period after surgery was 24 months (IQR:19.5-27) and 12 cases (19.05%) had recurrence.Conclusion: The modified hybrid technique eliminated the need for patients repositioning during the extravesical bladder cuff excision and permitted the continuity of the operation. It minimizes the operative time and eliminates the distortion of the surgeon's lower back. This technique can be safely reproduced with surgical outcomes comparable to other established techniques.