A new spectrophotometric method to detect residual amounts of peroxide after reprocessing hemodialysis filters

Abstract

A quantitative spectrophotometric test may improve detection of residues of peracetic acid when compared to the standard visual qualitative test. This innovation may contribute to the development of safer standards for reuse of hemodialysis filters.

Disinfectants in a Hemodialysis Setting: Antifungal Activity Against Aspergillus and Fusarium Planktonic and Biofilm Cells and the Effect of Commercial Peracetic Acid Residual in Mice

“…Among all disinfectants used in the hemodialysis environment, the peracetic acid-based disinfectants has been widely used both for the disinfection of machines between patient shifts and for the conditioning of dialyzers (reuse) between dialysis sessions ( Oliveira et al., 2011 ; Szewczyk et al., 2013 ; Rutala and Weber, 2015 ). Factors such as: decomposition into non-toxic and non-mutagenic products; efficiency even in the presence of organic residues; effectiveness in low doses and against a wide spectrum of antimicrobial agents have contributed to the choice of peracetic acid to replace sodium hypochlorite ( Rutala and Weber, 2015 ).…”

“…Several disinfectants such as acetic, citric, peracetic acids, sodium hypochlorite, and sodium metabisulfite have been used in the hemodialysis microenvironment for different purposes ( Sakuma et al., 2010 ; Oliveira et al., 2011 ; Bolasco et al., 2012 ; Kawanishi et al., 2016 ). National and international guidelines recommend that aqueous sodium hypochlorite solutions at 0.05%, which corresponds to 500 parts per million (ppm) with 30 minutes exposure period, are used to disinfect hemodialysis machines ( API, 2010 ; Brazil, 2014 ; Rutala and Weber, 2015 ).…”

“…The peracetic acid in mixtures with acetic acid, hydrogen peroxide, a stabilizer, and, sometimes, sulfuric acid has increased its use frequency in the dialysis setting ( Brazil, 2014 ; Rutala and Weber, 2015 ). In patient shifts, this disinfectant was used to the hemodialysis filters sterilization to allow their reuse and to the hemodialysis machines disinfection ( Oliveira et al., 2011 ). In dialysis facilities that perform reuse, the dialyzer is specific for the patient who can reuse it up to 15 times, on average ( Oliveira et al., 2011 ; Kreepala et al., 2017 ).…”

“…In patient shifts, this disinfectant was used to the hemodialysis filters sterilization to allow their reuse and to the hemodialysis machines disinfection ( Oliveira et al., 2011 ). In dialysis facilities that perform reuse, the dialyzer is specific for the patient who can reuse it up to 15 times, on average ( Oliveira et al., 2011 ; Kreepala et al., 2017 ). Lacson et al.…”

Riscos Ocupacionais Durante O Reprocessamento De Hemodialisadores

“…Dessa forma, surge também a colaboração com os aspectos laborais prevenindo a contaminação de quem manipular esses materiais. 13,14 Em ampla revisão sobre as complicações em hemodiálise, embora o enfoque seja o paciente e o processamento seja uma realidade nacional e internacional, complicações relacionadas ao reuso de filtros de diálise não são lembradas, seja com relação aos pacientes, seja aos trabalhadores. 15 Em outro estudo que investigou a percepção de riscos por 296 trabalhadores de enfermagem, 36,2% dos participantes citaram riscos relacionados a agentes químicos, entretanto a pesquisa não avançou na avaliação da percepção da dimensão desse risco e se a percepção condizia com o risco real.…”