A new simplified and accurate sa-SOFA score

Vacheron, Charles-Hervé; Friggeri, Arnaud; Iwaz, Jean; Allaouchiche, Bernard; Bohé, Julien; Monneret, Guillaume; Venet, Fabienne; Cour, Martin; Argaud, Laurent; Aubrun, Frédéric; Rimmelé, Thomas; Pachot, Alexandre; Piriou, Vincent; Lepape, Alain; Maucort‐Boulch, Delphine

doi:10.1016/j.jcrc.2019.11.009

Cited by 9 publications

(17 citation statements)

References 23 publications

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“…However, in the study of constructing the sa‐SOFA score, the predictive value of sa‐SOFA is better than SOFA. The reason is that the research inclusion criteria are different; the studies on sa‐SOFA showed the SOFA score predicted AUC of the 28‐day mortality only as 0.687 due to 22.1% of the included participants (316/1436) being SIRS patients 18 . The inclusion of SIRS patients is also one of the limitations recognized by the author 18 …”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, for the purpose of easy and effective practice, SOFA has been simplified into three different versions including simplified SOFA (sSOFA), 16 simplified organ dysfunction criteria optimized for electronic health records (eSOFA), 17 and simplified and accurate SOFA (sa‐SOFA), 18 which contained slightly more parameters than qSOFA to avoid the disadvantages that qSOFA presented. Researchers have shown that the predictability of sepsis using these three simplified SOFA scores are similar to or better than that of SOFA.…”

Section: Introductionmentioning

confidence: 99%

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External validation and comparison of two versions of simplified sequential organ failure assessment scores to predict prognosis of septic patients

Shi

Zhang

et al. 2021

Int J Clinical Practice

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Background Evidence shows that simplified SOFA scoring system has better clinical practice. Objective This study aimed to validate and compare the scores acquired with simplified organ dysfunction criteria optimized for electronic health records (eSOFA), and simplified and accurate sequential organ failure assessment (sa‐SOFA) for their accuracies in predicting the prognosis of septic patients. Methods This retrospective observational study was conducted at three major academic hospitals. Clinical data from 574 patients diagnosed with sepsis following the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis‐3)were retrospectively retrieved and analysed. Scores from the quick sequential organ failure assessment (qSOFA) and sequential organ failure assessment (SOFA) were used as reference scores. The area under the receiver operating characteristic curve (AUROC) was used to assess the performance of eSOFA and sa‐SOFA scores in predicting in‐hospital mortality. Results AUROC analysis demonstrated the predictability of the four scoring systems for sepsis surveillance, listed in descending order as: sa‐SOFA, 0.790 (95% confidence interval [CI]: 0.754‐0.822); SOFA, 0.774 (95% CI: 0.738‐0.808); eSOFA, 0.729 (95% CI: 0.691‐0.765); and qSOFA, 0.618 (95% CI: 0.577‐0.658). Moreover, sa‐SOFA and SOFA scores (Z = 1.950, P = .051) did not significantly differ from each other in discriminatory power, but the sa‐SOFA score had a higher power than eSOFA score (P values < .001). Conclusion sa‐SOFA appeared to have performed better than eSOFA score for predicting in‐hospital mortality in patients’ sepsis. Further large prospective studies are needed to externally validate.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

External validation and comparison of two versions of simplified sequential organ failure assessment scores to predict prognosis of septic patients

Shi

Zhang

et al. 2021

Int J Clinical Practice

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“…The Sequential Organ Failure Assessment (SOFA) score is a mortality prediction score that is based on the degree of dysfunction of six organ systems 47,48 .…”

Section: Sequential Organ Failure Assessment Scorementioning

confidence: 99%

Multiorgan failure during COVID-19 pandemic in cardiovascular patients. Role of advanced cardiac and pulmonary support

Barbagelata¹,

Giorgi²,

Koerner³

et al. 2020

RACI

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COVID-19 has now claimed several thousands of lives and overwhelmed the healthcare systems of several countries. Patients with cardiovascular disease are at particular risk not just of the infection itself but of its cardiac complications. Compared to other hospitalized patients with COVID-19, those needing intensive care, are more likely to have preexisting cardiovascular diseases or risk factors. Cytokine storm with hyperinflammation correlates with the severity of the disease. It is associated with mortality and is a key factor in determining the clinical course of extrapulmonary multiple-organ failure, suggesting that the inflammatory storm is associated with damage in extrapulmonary tissues and organs. Advanced Cardiac and Pulmonary Support has been reported in selected a COVID population.

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“…Una escala de Sa-SOFA en aumento debe alertarnos de que la evolución del paciente no es la adecuada e identifica el órgano al que debemos prestar atención (Tabla 1). 5 RESPUESTA MOTOR: uno de los componentes de mayor valor predictivo pronóstico de la escala de SOFA proviene de su componente neurológico. Sin mencionar que la preservación del cerebro es una de nuestras principales metas aún más allá de la supervivencia.…”

Section: Introductionunclassified

“…RASS = al estado neurológico: respuesta motora y ocular. Escala de SOFA-simplificado de Vacheron CH, et al5 …”

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Certeza diagnóstica del SOFA-simplificado en pacientes con COVID-19 en Unidad de Terapia Intensiva del Centro Médico ABC

Bejarano¹,

Gutiérrez²,

Aguirre-Sánchez³

et al. 2021

Medicina Crítica

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A new simplified and accurate sa-SOFA score

Cited by 9 publications

References 23 publications

External validation and comparison of two versions of simplified sequential organ failure assessment scores to predict prognosis of septic patients

External validation and comparison of two versions of simplified sequential organ failure assessment scores to predict prognosis of septic patients

Multiorgan failure during COVID-19 pandemic in cardiovascular patients. Role of advanced cardiac and pulmonary support

Certeza diagnóstica del SOFA-simplificado en pacientes con COVID-19 en Unidad de Terapia Intensiva del Centro Médico ABC

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