A New SET Piece in Cancer Development

Abstract

Targeting IFN alpha to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance. Nat Commun 2018;9. 20. Sun ZC, Ren ZH, Yang KT, et al. A next-generation tumor-targeting IL-2 preferentially promotes tumorinfiltrating CD8(þ) T-cell response and effective tumor control. Nat Commun 2019;10.