A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA.

The Relationship Between Parental Alcoholism and Adolescent Psychopathology: A Systematic Examination of Parental Comorbid Psychopathology

“…The reliability of the SSAGA has been examined in the COGA sample both within and across the six centers. Test-retest reliabilities (kappas) have been found to range from .65 to .90 and from .74 to 1.00, within centers and across centers, respectively, for the diagnoses examined in the current study (Bucholz et al, 1994). The individual criterion items of the SSAGA also have been shown to be highly reliable in the COGA sample (Bucholz et al, 1995).…”

“…All of the participants in this study were involved in the Collaborative Study on the Genetics of Alcoholism (COGA; Begleiter et al, 1995;Bucholz et al, 1994). This large-scale, extended family study includes six center sites (Indiana University; State University of New York; University of California at San Diego; University of Connecticut; University of Iowa; and Washington University in St. Louis) and was designed to identify susceptibility genes for alcohol dependence.…”

“…The SSAGA is a clinical diagnostic psychiatric interview derived from the National Institutes of Mental Health Diagnostic Interview Schedule (DIS; Robins et al, 1985), The Structured Clinical Interview for DSM-III-R (Spitzer, Williams, Gibbon, & First, 1992), The Schedule for Affective Disorders and Schizophrenia (SADS; Endicott & Spitzer, 1978), The Composite International Diagnostic Interview , and The HELPER Interview (Coryell, Cloninger, & Reich, 1978). The SSAGA has good reliability and validity characteristics (Bucholz et al, 1994;Hesselbrock, Easton, Bucholz, Schuckit, & Hesselbrock, 1999). The reliability of the SSAGA has been examined in the COGA sample both within and across the six centers.…”

Externalizing disorders in the offspring from the San Diego prospective study of alcoholism

“…The 10-year follow-up instrument for probands and spouses was based on questions derived from the Schedule of Affective Disorders and Schizophrenia (SADS), along with changes consistent with subsequent versions of that instrument (Spitzer and Endicott, 1977;Spitzer et al, 1992). Items in the 15-year interview and beyond were expanded to cover additional information using questions taken from the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) interview (Bucholz et al, 1994;Hesselbrock et al, 1999). Beginning with the 15-year follow-up, adult children were evaluated using an instrument similar to the proband follow-up, while younger offspring beginning at age 12 were administered the face-to-face SSAGA interviews developed for adolescents, known as the C-SSAGA-A (Barnow et al, 2002;Kuperman et al, 2001), using diagnoses from the Third Revised Diagnostic and Statistical Manual of the American Psychiatric Association (DSM-III-R) (American Psychiatric Association, 1987).…”

Ionotropic glutamate receptor gene GRIK3 SER310ALA functional polymorphism is related to delirium tremens in alcoholics

“…All patients were older than 18 years and met ICD10 and DSM-IV criteria for alcohol dependence. Previous and current epileptic seizures, delirious symptoms such as hallucinations or severe disturbance of consciousness were assessed with a structured interview (SSAGA: Semi-Structured Assessment for the Genetics of Alcoholism 51,52 ). Personality diagnosis, including antisocial personality disorder, was assessed using the SCID II interview (German Version 53 ).…”